「c2」の検索結果

Planner→Builder→EvaluatorのLong-Runningエージェントハーネスで複雑なタスクを実装します。plannerがfeatures.jsonに機能を分解し、builderがTDDで1機能ずつ実装し、evaluatorがPASSするまでbuilderを繰り返します。「〇〇を作って」「実装して」「long-running」などのリクエストで起動します。

Iteratively detects and auto-fixes technical debt in a codebase using three quality criteria from debt-analysis references: conditional branch simplification, encapsulation, and separation of concerns. Applies fixes directly to code, runs existing tests to verify no regressions, re-analyzes, and loops until all high-severity issues are resolved or max iterations (5) reached. Use this skill when you want to automatically improve code quality with real code changes, reduce technical debt systematically, or clean up code to meet quality standards. Trigger on phrases like "fix technical debt", "clean up code quality", "refactor and fix issues", "improve code quality automatically", "apply debt fixes", "fix code problems", "eliminate debt".

日本語の概要は準備中です。原文の説明を表示しています。

t-wada式TDD（テスト駆動開発）でRED→GREEN→REFACTORサイクルを使ってテストファーストで開発を進めるスキル。 ユーザーが「TDDで実装して」「テストファーストで」「t-wada式で」「REDから始めて」「失敗するテストを先に」と言った場合は必ずこのスキルを使うこと。 FizzBuzz、スタック、認証、バリデーションなど、あらゆる実装タスクにTDDアプローチを適用できる。 ユーザーが実装を始めようとしているときは積極的にTDDを提案すること。

Uncorrelated Evaluator — 4軸ルーブリック専門エージェント（functionality-reviewer・code-reviewer・design-reviewer・originality-reviewer）と security-reviewer を5並列実行し、成果物を多面的に独立評価します。PASS / NEEDS WORK / BLOCKED 判定を返します。Self-leniency 防止のため、実装エージェントのコンテキストを引き継がない新規エージェントとして起動します。「レビューして」「評価して」「実装を確認して」などのリクエストで起動します。

Analisa custo AWS e identifica desperdício em EC2, RDS, S3, EKS, EBS, Elastic IP, NAT Gateway e tráfego. Use quando o usuário disser "custo", "fatura", "está caro", "FinOps", "reduzir gasto AWS", "Cost Explorer", "otimizar custo". Quase todo leitura — seguro por natureza.

日本語の概要は準備中です。原文の説明を表示しています。

Arquitetura e diagnóstico AWS — VPC, EC2, ECS, EKS, ALB, NLB, RDS, ElastiCache, S3, CloudFront, Route53, IAM, WAF, GuardDuty. Use quando o usuário disser "AWS", "VPC", "ALB", "RDS", "revisar a arquitetura", "Well-Architected", "subnet", "security group", "IAM", ou citar qualquer serviço AWS. Leitura livre; qualquer mudança passa pelo portão de confirmação.

日本語の概要は準備中です。原文の説明を表示しています。

Loads, converts, and manipulates Hi-C contact matrices in cooler format (.cool/.mcool/.scool) and Juicer .hic, using cooler (Python + CLI), hic2cool, and hictk. Covers the single-resolution mcool URI (file.mcool::/resolutions/<bp>), the load-bearing divisive-vs-multiplicative weight-naming rule (KR/VC/VC_SQRT auto-divisive vs cooler's multiplicative weight), what survives .hic<->.cool conversion (FRAG matrices and norm vectors do not), raw-vs-balanced coarsening, the .pairs upper-triangle/chromsize-order contract, and chrom-naming/bin-table provenance. Use when loading a cooler, converting .hic to .mcool, selecting a resolution, building a cooler from pairs or a matrix, coarsening/zoomifying, importing Juicer norm vectors, or debugging all-NaN balanced matrices and chr1-vs-1 empty fetches.

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Predict peptide-MHC class II (HLA-DR/DQ/DP) binding and presentation for CD4 T-cell epitopes with NetMHCIIpan-4.3 and MixMHC2pred-2.0. Covers why class II is far less reliable than class I (open binding groove, 9-mer register ambiguity, sparse noisy training data, DR>DP>DQ accuracy asymmetry), the DQ/DP heterodimer alpha/beta pairing trap, and the looser 1%/5% %Rank thresholds. Use when predicting CD4 epitopes for vaccine help, mapping class II neoantigens, or scoring long peptides against DR/DQ/DP. For CD8/class I see mhc-binding-prediction.

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Tests genotype-environment associations and identifies adaptive loci while correcting for the four-confound landscape (structure, demography, background selection, sampling design) using LFMM2 with mandatory K via sNMF cross-entropy elbow (LEA 3), BayPass Core/AUX/C2/IS with Omega covariance matrix, RDA / pRDA for polygenic adaptation (Forester 2018; requires imputed genotypes), OutFLANK with trimmed FST null, pcadapt, gradient forests (Ellis-Smith-Pitcher 2012, NOT mis-cited Ellis-Manel), Capblancq & Forester 2021 RDA Swiss-army-knife, genomic-offset prediction with Lind & Lotterhos 2025 three-regime caveat, Lotterhos-Whitlock sampling optima, Wang & Bradburd 2014 IBD vs IBE, and Circuitscape + ResistanceGA. Use when identifying adaptive loci across gradients, choosing K for LFMM2, deciding among GEA methods, predicting maladaptation with the novel-environment caveat, distinguishing IBD vs IBE, or optimizing sampling design.

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Resolve subclonal copy number, whole-genome doubling, and copy-number tumor evolution from bulk sequencing with Battenberg, TITAN, and MEDICC2. Covers clonal versus subclonal copy-number states, haplotype phasing for subclonal resolution, cancer cell fraction, whole-genome-doubling detection and timing relative to mutations, mirrored subclonal allelic imbalance, and copy-number phylogenies. Use when a tumor is heterogeneous and bulk data shows non-integer copy number, when calling subclonal CNAs, detecting or timing whole-genome doubling, reconstructing copy-number evolution, or deciding between Battenberg and TITAN.

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Assesses ChIP-seq quality across antibody specificity, fragmentation, enrichment, replicate concordance, and library complexity. Computes FRiP, NSC/RSC (phantompeakqualtools), library complexity (NRF/PBC1/PBC2), deepTools plotFingerprint (JS distance, AUC, synthetic JS), ChIPQC, IDR with ENCODE Nself/Nt rules, and detects hyper-ChIPable artifacts. Use when validating an antibody, diagnosing failed peak calls, deciding whether to proceed with downstream analysis, grading against ENCODE thresholds, or auditing replicate concordance.

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Performs structure-based virtual screening using AutoDock Vina, SMINA, GNINA (CNN scoring), and DiffDock-L hybrid workflows with explicit choice rules across rigid vs flexible docking, cross-docking vs self-docking, binding-site detection (P2Rank, fpocket), receptor preparation (PDB2PQR, PROPKA), ligand preparation (meeko, OpenBabel), and ultralarge-library screening (ZINC22, Enamine REAL). Use when screening chemical libraries against a protein target to find candidate binders, ranking docking poses, or selecting a docking workflow for a specific scenario.

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ATAC-seq library quality control -- TSS enrichment, FRiP, fragment-size periodicity, library complexity (NRF/PBC1/PBC2), mitochondrial fraction, and ENCODE 4 thresholds. Use when assessing whether an ATAC-seq library passes ENCODE acceptance criteria, diagnosing transposition artefacts, comparing Omni-ATAC vs standard prep quality, or selecting which replicates to drop before peak calling.

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Analyzes differential transcript usage (DTU) and isoform switches with functional consequence prediction (NMD via 50nt rule, ORF disruption, protein domain loss/gain, signal peptide changes, IDR alterations, coding-potential shifts). Tools include IsoformSwitchAnalyzeR v2 (auto-selects satuRn for >5 reps else DEXSeq), the manual DRIMSeq -> DEXSeq/satuRn -> stageR DTU pipeline, and fishpond/swish for inferential-uncertainty-aware DTE. Distinguishes DTU from DGE and DTE; integrates external annotators (CPC2, Pfam, SignalP, IUPred2A or DeepTMHMM). Use when investigating how splicing differences alter protein function or trigger NMD-mediated degradation.

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Regulatory review across 14 frameworks — compliance review, privacy impact assessment, regulatory gap analysis, data subject rights, consent mechanisms, audit trail, AI ethics review, data flow mapping. Covers GDPR, PIPEDA, HIPAA, PCI-DSS, SOC2, UAE-PDPL, EU AI Act and more.

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Expert security auditor specializing in DevSecOps, comprehensive cybersecurity, and compliance frameworks. Masters vulnerability assessment, threat modeling, secure authentication (OAuth2/OIDC), OWASP standards, cloud security, and security automation. Handles DevSecOps integration, compliance (GDPR/HIPAA/SOC2), and incident response. Use PROACTIVELY for security audits, DevSecOps, or compliance implementation.

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You are a compliance expert specializing in regulatory requirements for software systems including GDPR, HIPAA, SOC2, PCI-DSS, and other industry standards. Perform comprehensive compliance audits and provide implementation guidance for achieving and maintaining compliance.

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This skill teaches security teams how to detect and respond to unauthorized cryptocurrency mining operations in cloud environments. It covers identifying cryptomining indicators through compute usage anomalies, network traffic patterns to mining pools, GuardDuty CryptoCurrency findings, and runtime process monitoring on EC2, ECS, EKS, and Azure Automation workloads.

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Performs statistical analysis of Zeek conn.log connection intervals to detect C2 beaconing patterns. Uses the ZAT library to load Zeek logs into Pandas DataFrames, calculates inter-arrival time standard deviation, and flags periodic connections with low jitter. Use when hunting for command-and-control callbacks in network data.

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Systematically deobfuscate multi-layer PowerShell malware using AST analysis, dynamic tracing, and tools like PSDecode and PowerDecode to reveal hidden payloads and C2 infrastructure.

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This skill teaches security teams how to deploy and operationalize Amazon GuardDuty for continuous threat detection across AWS accounts and workloads. It covers enabling protection plans for S3, EKS, EC2 runtime monitoring, and Lambda, interpreting finding severity levels, and building automated response workflows using EventBridge and Lambda.

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Detect PowerShell Empire framework artifacts in Windows event logs by identifying Base64 encoded launcher patterns, default user agents, staging URL structures, stager IOCs, and known Empire module signatures in Script Block Logging events.

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Build an automated system to track adversary infrastructure using passive DNS, certificate transparency, WHOIS data, and IP enrichment to map and monitor threat actor command-and-control networks.

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Analyzes network traffic captures and flow data to identify adversary activity during security incidents, including command-and-control communications, lateral movement, data exfiltration, and exploitation attempts. Uses Wireshark, Zeek, and NetFlow analysis techniques. Activates for requests involving network traffic analysis, packet capture investigation, PCAP analysis, network forensics, C2 traffic detection, or exfiltration detection.

日本語の概要は準備中です。原文の説明を表示しています。