Download ENCODE genomics files (BED, FASTQ, BAM, bigWig, etc.) to the user's machine. Use when the user wants to download data files from ENCODE experiments.
日本語の概要は準備中です。原文の説明を表示しています。
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概要と使いどころ
Download ENCODE genomics files (BED, FASTQ, BAM, bigWig, etc.) to the user's machine. Use when the user wants to download data files from ENCODE experiments.
日本語の概要は準備中です。原文の説明を表示しています。
Detect ranking drops and lost traffic using Google Search Console data. Compares the last 28 days against the prior 28-day period to surface pages and keywords with the biggest declines. Use when user says "GSC drops", "ranking drops", "lost traffic", "pages losing rankings", or "keyword drops".
日本語の概要は準備中です。原文の説明を表示しています。
Use when a task needs the judgment of a Computer Systems Analyst — running requirements elicitation and gap analysis against a target system, writing a feasibility study for a build-vs-buy-vs-customize decision, designing a system integration approach (point-to-point vs middleware vs API-led), scoping data-migration risk before a cutover, or choosing between phased and big-bang implementation strategies.
日本語の概要は準備中です。原文の説明を表示しています。
Generate a production-grade OEE (Overall Equipment Effectiveness) measurement pipeline for a manufacturing line — data ingestion from MQTT/OPC-UA/Modbus/CSV, A×P×Q calculation engine, Six Big Losses categorizer, MTBF/MTTR/TEEP metrics, Grafana or Streamlit dashboard.
日本語の概要は準備中です。原文の説明を表示しています。
Distill large models into smaller ones — teacher-student training, data generation, loss design, and quality validation. Use when you need big-model behavior at small-model cost.
日本語の概要は準備中です。原文の説明を表示しています。
Calls m6A peaks from MeRIP-seq / m6A-seq paired IP-vs-input data using exomePeak2 (transcript-aware, GC-bias-corrected Poisson GLM), MeTPeak (HMM over sliding windows), MACS3/MACS2 with --nomodel --broad --keep-dup all (genome-wide broad alternative), and DRACH motif enrichment via HOMER or ggseqlogo as a sanity check (NOT a filter). Covers BED12 vs narrowPeak output, exonic vs intronic peak handling, multi-tool reconciliation (intersection vs union), the m6A-vs-m6Am ambiguity at 5'UTR peaks that antibody methods cannot resolve, and orthogonal validation (miCLIP/GLORI/m6A-SAC-seq/m6Anet). Use when calling peaks from paired IP/input genome BAMs, choosing exomePeak2 (transcript-aware default) vs MACS3 (broad genomic) vs MeTPeak (HMM-smoothed low-coverage), confirming DRACH enrichment as a sanity check on the peak set, reconciling differing peak sets across tools, validating MeRIP peaks against single-base methods, interpreting 5' peaks where m6Am contamination is possible, or recommending a consensus strategy.
日本語の概要は準備中です。原文の説明を表示しています。
Build genome-browser-style multi-track figures with pyGenomeTracks (config-driven), Gviz (R), and IGV batch screenshotting. Covers BigWig coverage tracks, BED/peak overlays, gene-model rendering, Hi-C matrix tracks, BedPE link arcs, spike-in-aware normalization, and the bamCoverage --normalizeUsing trap. Use when producing publication figures of genomic loci with stacked aligned tracks (coverage, peaks, genes, interactions) for ChIP-seq, ATAC-seq, RNA-seq, Hi-C, or generic locus visualization.
日本語の概要は準備中です。原文の説明を表示しています。
Visualizes ChIP-seq data using deepTools (computeMatrix, plotHeatmap, plotProfile, bamCoverage, bamCompare), pyGenomeTracks (modern INI-driven track plots), Gviz (R browser-style), EnrichedHeatmap (ComplexHeatmap-based), ChIPseeker tag heatmaps, and IGV batch screenshots. Handles bigWig normalization choices (CPM, BPM, RPGC, spike-in scaled), bamCompare operations (log2 ratio, subtract) with SES scaling, k-means clustering of heatmaps for biological subgrouping, and spike-in-scaled tracks for global-shift experiments. Use when generating publication-quality ChIP-seq signal heatmaps, profile plots, genome-browser tracks, or comparing samples visually.
日本語の概要は準備中です。原文の説明を表示しています。
### 1. The Fault/Error/Failure Hierarchy NOT for unrelated tasks outside this domain.
日本語の概要は準備中です。原文の説明を表示しています。
Transform client hearing sheets and meeting notes into structured requirements documents. Use when converting raw hearing data (Japanese/English) into formal requirements, generating traceability matrices, identifying gaps/ambiguities, and mapping requirements to WBS items. Triggers include "hearing to requirements", "meeting notes to specs", "requirements traceability", "gap analysis for requirements", or requests involving hearing sheet analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Use when: architecture mode, architect this, ADR, C4, PlantUML, system boundary, design decision, PRD gap, high ambiguity, multiple technical approaches, security architecture, data architecture, integration risk, implementability gap, story ticket, or epic ticket.
日本語の概要は準備中です。原文の説明を表示しています。
Create a PostHog endpoint with the right shape on the first try — covers query kind choice, name conventions, what to expose as variables (HogQL code_name vs insight breakdown), data_freshness_seconds, and whether to materialise on day one. Use when the user says "create an endpoint", "expose this query as an API", "turn this insight into an endpoint", or asks for help structuring a new endpoint. Steers away from common mistakes: materialising a query with cohort breakdowns or compare mode, inline-only variables on a materialised endpoint, unbounded date ranges, ambiguous names.
日本語の概要は準備中です。原文の説明を表示しています。
Build genome-browser-style multi-track figures with pyGenomeTracks (config-driven), Gviz (R), and IGV batch screenshotting. Covers BigWig coverage tracks, BED/peak overlays, gene-model rendering, Hi-C matrix tracks, BedPE link arcs, spike-in-aware normalization, and the bamCoverage --normalizeUsing trap. Use when producing publication figures of genomic loci with stacked aligned tracks (coverage, peaks, genes, interactions) for ChIP-seq, ATAC-seq, RNA-seq, Hi-C, or generic locus visualization.
日本語の概要は準備中です。原文の説明を表示しています。
Optimize ToolUniverse skills for better report quality, evidence handling, and user experience. Apply patterns like tool verification, foundation data layers, disambiguation-first, evidence grading, quantified completeness, and report-only output. Use when reviewing skills, improving existing skills, or creating new ToolUniverse research skills.
日本語の概要は準備中です。原文の説明を表示しています。
Reads a specific actor's live telemetry from a running CARLA server — location and rotation, velocity and speed, acceleration, angular velocity, and for vehicles the control input (throttle/steer/brake), front-wheel steer angle and mass. All kinematics come from one world snapshot so they are frame-consistent. Use when the user asks "how fast is it going", "where/what heading is the car", "show the ego's telemetry", or "stream a vehicle's state". Resolve ambiguous targets with the world-data skill.
日本語の概要は準備中です。原文の説明を表示しています。
Fighter-jet / helicopter head-up display: phosphor green on near-black, all-caps data overlays, angular geometry. Zero ambiguity at speed and altitude. For flight-sim UIs, telemetry, and command-and-control displays.
日本語の概要は準備中です。原文の説明を表示しています。
Predict peptide-MHC class II (HLA-DR/DQ/DP) binding and presentation for CD4 T-cell epitopes with NetMHCIIpan-4.3 and MixMHC2pred-2.0. Covers why class II is far less reliable than class I (open binding groove, 9-mer register ambiguity, sparse noisy training data, DR>DP>DQ accuracy asymmetry), the DQ/DP heterodimer alpha/beta pairing trap, and the looser 1%/5% %Rank thresholds. Use when predicting CD4 epitopes for vaccine help, mapping class II neoantigens, or scoring long peptides against DR/DQ/DP. For CD8/class I see mhc-binding-prediction.
日本語の概要は準備中です。原文の説明を表示しています。
Calls m6A peaks from MeRIP-seq / m6A-seq paired IP-vs-input data using exomePeak2 (transcript-aware, GC-bias-corrected Poisson GLM; Liu 2022 *NAR Genom Bioinform* 4:lqac046), MeTPeak (HMM over sliding windows; Cui 2016 *Bioinformatics* 32:i378), MACS3 / MACS2 with --nomodel --broad --keep-dup all (genome-wide broad alternative), and DRACH motif enrichment confirmation via HOMER or ggseqlogo as a sanity check (NOT a filter). Covers BED12 vs narrowPeak output formats, exonic vs intronic peak handling, multi-tool reconciliation (intersection vs union; cross-caller IDR-equivalent), the m6A-vs-m6Am ambiguity at 5'UTR peaks that antibody-based methods cannot resolve, and orthogonal-validation routes (miCLIP / GLORI / m6A-SAC-seq / m6Anet). Use when calling peaks from paired IP/input genome BAMs, choosing exomePeak2 (transcript-aware default) vs MACS3 (broad genomic) vs MeTPeak (HMM-smoothed low-coverage), confirming DRACH enrichment as a sanity check on the peak set as a whole, reconciling differing peak sets across tools, validating MeRIP peaks against orthogonal single-base methods, interpreting peaks at the 5' end where m6Am contamination is possible, or recommending a multi-tool consensus strategy.
日本語の概要は準備中です。原文の説明を表示しています。
Build genome-browser-style multi-track figures with pyGenomeTracks (config-driven), Gviz (R), and IGV batch screenshotting. Covers BigWig coverage tracks, BED/peak overlays, gene-model rendering, Hi-C matrix tracks, BedPE link arcs, spike-in-aware normalization, and the bamCoverage --normalizeUsing trap. Use when producing publication figures of genomic loci with stacked aligned tracks (coverage, peaks, genes, interactions) for ChIP-seq, ATAC-seq, RNA-seq, Hi-C, or generic locus visualization.
日本語の概要は準備中です。原文の説明を表示しています。
Visualizes ChIP-seq data using deepTools (computeMatrix, plotHeatmap, plotProfile, bamCoverage, bamCompare), pyGenomeTracks (modern INI-driven track plots), Gviz (R browser-style), EnrichedHeatmap (ComplexHeatmap-based), ChIPseeker tag heatmaps, and IGV batch screenshots. Handles bigWig normalization choices (CPM, BPM, RPGC, spike-in scaled), bamCompare operations (log2 ratio, subtract, SES), k-means clustering of heatmaps for biological subgrouping, and spike-in-scaled tracks for global-shift experiments. Use when generating publication-quality ChIP-seq signal heatmaps, profile plots, genome-browser tracks, or comparing samples visually.
日本語の概要は準備中です。原文の説明を表示しています。
Splits one big Claude task or automation into a set of focused AI Matrx agents that work on the person's own AI Matrx tables, then builds and test-runs each one. Use when the person says "split my task into agents", "turn my automation into AI Matrx agents", "make agents for my work", or after their data has moved into AI Matrx.
日本語の概要は準備中です。原文の説明を表示しています。
Temu, SHEIN, AliExpress, and TikTok product selection big data analysis agent. Identify trending products, analyze competition, estimate demand, and find sourcing opportunities across fast-fashion and marketplace platforms. Triggers: temu product selection, shein product research, aliexpress trending, tiktok shop products, temu selector, fast fashion products, temu trending, shein trends, product sourcing, dropshipping products, temu winning products
日本語の概要は準備中です。原文の説明を表示しています。
Master enterprise-grade Scala development with functional programming, distributed systems, and big data processing. Expert in Apache Pekko, Akka, Spark, ZIO/Cats Effect, and reactive architectures. Use PROACTIVELY for Scala system design, performance optimization, or enterprise integration.
日本語の概要は準備中です。原文の説明を表示しています。
### 1. The Fault/Error/Failure Hierarchy NOT for unrelated tasks outside this domain.
日本語の概要は準備中です。原文の説明を表示しています。