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概要と使いどころ
Recommends adding intravenous bisphosphonate or denosumab when hypercalcemia due to parathyroid carcinoma is not adequately controlled with a calcimimetic. Consider this adjunct when a clinician notes persistent HCM despite calcimimetic therapy and asks about next-step therapy.
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This skill suggests treatment with either a calcimimetic or an intravenous bisphosphonate/denosumab for hypercalcemia due to parathyroid carcinoma. Triggered when a clinician diagnoses parathyroid carcinoma-associated hypercalcemia of malignancy and inquires about initial medical management options.
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Expert-level calculus knowledge. Use when working with limits, derivatives, integrals, multivariable calculus, vector calculus, differential equations, series, or optimization. Also use when the user mentions 'derivative', 'integral', 'limit', 'chain rule', 'gradient', 'divergence', 'curl', 'Taylor series', 'Fourier series', 'partial derivative', 'double integral', 'line integral', 'Stokes theorem', or 'Lagrange multipliers'.
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Calculate and model paid-media CPA, CPL, CPC, CPM, ROAS, MER, break-even targets, contribution margin, LTV:CAC, impression-share opportunity, budgets, forecasts, and experiment economics. Use for PPC math, ad calculator, break-even analysis, ROAS calculator, CPA calculator, budget forecast, LTV CAC, or MER.
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Create, open or edit Calc spreadsheets: ODS default; XLSX for Excel compatibility.
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Manage cost basis calculation in TRES Finance: check status, view/change strategy (FIFO, LIFO, AVG, MAX_GAINS, MAX_LOSSES, FIFO_IMPAIRMENT), trigger recalculation, review financial issues, manage reevaluations/impairments, set bulk fiat prices, configure spec-ID lot disposal rules, view per-asset cost basis results, and export cost basis reports. Trigger this skill whenever the user asks about cost basis, gains/losses, realized gains, unrealized gains, COGS, inventory lots, tax lots, cost basis strategy, reevaluation, impairment, fiat value override, spec-ID rules, financial issues (negative balance, missing fiat), or anything related to how their crypto assets are costed. Also trigger when the user says "calculate cost basis", "what is my cost basis strategy", "show me financial issues", "create a reevaluation", "run cost basis", "change strategy to LIFO", or similar.
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TikTok Shop profit margin calculator for sellers. Calculate cost breakdowns including affiliate commissions, platform fees, and FBT costs. Includes return rate analysis for impulse buying patterns. No API key required.
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Shopify/DTC profit margin calculator for sellers. Calculate cost breakdowns including ad spend, CAC, payment processing fees, and 3PL costs. Includes LTV/CAC analysis and DTC-specific benchmarks. No API key required.
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Walmart profit margin calculator for sellers. Calculate cost breakdowns including WFS fulfillment, storage fees, and referral fees. Includes comparison with Amazon FBA and lower competition advantage analysis. No API key required.
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This package implements functions to find influential TF and target based on different input type. It have five module: Multi-peak multi-gene annotaion(mmPeakAnno module), Calculate regulation potential(calcRP module), Find influential Target based on ChIP-Seq and RNA-Seq data(Find influential Target module), Find influential TF based on different input(Find influential TF module), Calculate peak-gene or peak-peak correlation(peakGeneCor module). And there are also some other useful function lik
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MSA2dist calculates pairwise distances between all sequences of a DNAStringSet or a AAStringSet using a custom score matrix and conducts codon based analysis. It uses scoring matrices to be used in these pairwise distance calcualtions which can be adapted to any scoring for DNA or AA characters. E.g. by using literal distances MSA2dist calculates pairwise IUPAC distances.
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Universal tariff calculator for Amazon sellers. Calculate import duties, landed costs, and VAT/GST for any trade route. Supports CN→US, CN→EU, US→EU, EU→US, US→CN and custom origin/destination pairs. Includes Section 301 tariffs, trade agreement rates (USMCA, EVFTA), and HS code lookup. No API key required.
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Amazon PPC campaign builder and optimizer for sellers. Two modes: (A) Build — design a complete campaign structure from scratch with keyword groupings, bid calculations, and negative keyword lists, (B) Optimize — audit existing campaigns using search term reports, identify keyword funnel opportunities, calculate bid adjustments, and generate a week-by-week action plan. Integrates with amazon-keyword-research for keyword input. No API key required. Use when: (1) setting up Amazon PPC campaigns for a new product, (2) auditing existing campaign performance and ACoS, (3) optimizing keyword bids and negative keywords, (4) building Auto/Manual/Exact campaign structures, (5) analyzing search term reports for opportunities, (6) calculating break-even ACoS and target ACoS, (7) scaling profitable campaigns to Sponsored Brands or Display.
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Estimate pages needed for topical authority. Go/no-go decision before investing months in content. Triggers on: "how much content do I need", "topical authority estimate", "content moat", "how many articles", "content gap analysis", "can I compete in this niche", "content investment calculator", "is this niche worth the effort", "SEO feasibility", "how many pages to rank", "content volume needed", "competitive content analysis", "moat calculation", "authority gap", "should I invest in this niche".
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Standard business metric calculation with industry benchmarks. Use when calculating SaaS metrics (MRR, churn, LTV, CAC), e-commerce KPIs, or product analytics metrics with proper definitions.
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Calculate simple mathematical expressions using shell commands. Use when the user asks to perform arithmetic calculations like addition, subtraction, multiplication, division, or more complex math expressions.
日本語の概要は準備中です。原文の説明を表示しています。
Calculate mathematical expressions using shell commands. Use when the user asks to perform arithmetic calculations like addition, subtraction, multiplication, division, or powers.
日本語の概要は準備中です。原文の説明を表示しています。
Apply risk metrics calculation in reproducible local data workflows with version-aware APIs, explicit assumptions, and validation. Use when the user chooses risk metrics calculation or its strengths fit the task.
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侍酒师与葡萄酒 (侍酒师 / 葡萄酒 (Sommelier & Wine) — 葡萄酒鉴赏 + 侍酒服务的职业认知操作系统，从业者/侍酒师/学习者视角。覆盖: (a) 两大认证体系张力 — WSET (Wine & Spirit Education Trust, 英国, 知识+SAT 系统化品鉴方法, Diploma/L4 笔试导向) vs Court of Master Sommeliers (CMS, 美/英, 服务+盲品演绎法+理论三位一体, MS 头衔), 外加 Institute of Masters of Wine (MW, 学术研究+论文) 与 UC Davis 葡萄酒学/葡萄栽培学学院派; (b) 盲品 = 纯 tacit 校准技能 — 演绎品鉴网格 (deductive tasting: 看色/闻香/品味 → 结构线索 calculated structure → 推断品种/产区/年份/酒龄), WSET SAT vs CMS deductive grid 两套方法论; (c) 第一性张力 — codifiable 理论层 (产区/品种/酒法/风土/酿造/葡萄栽培) ⇄ tacit 校准层 (品鉴味觉记忆/盲品/侍酒服务), 这行的核心矛盾是「可背诵的知识」与「不可言传的味觉」之间; (d) 旧世界 vs 新世界框架 — 旧世界以风土/法定产区为组织原则 (AOC/DOCG/QbA 分级法), 新世界以品种为标签; 风土 (terroir) 是核心组织概念; (e) 侍酒服务/酒店层 — 餐厅 floor 的配餐 (food pairing)、醒酒/侍酒温度、酒单与酒窖管理、by-the-glass 与饮品项目经济学、盲品 service exam; (f) 葡萄酒商业层 — 三级分销体系 (美国 three-tier)、定价/配额 (allocation)、期酒 (en primeur)、投资酒 (Liv-ex) 与拍卖; (g) 智识/品味演进 — 帕克百分制 (Robert Parker / Wine Advocate 100-point) vs Jancis Robinson 20 分制散文派; 经典派 vs 现代派酿造; 自然酒/低干预 (natural/minimal-intervention) vs 传统技术派. 学派分歧: WSET 知识体系派 vs CMS 服务盲品派、旧世界风土派 vs 新世界品种/技术派、自然酒派 vs 传统派、百分制点评派 vs 散文叙述派、经典平衡派 vs 浓郁现代派. 不含: 家庭自酿 DIY 套件、纯调酒/鸡尾酒/烈酒、葡萄园重型农机工程、酒精成瘾/公共卫生政策、酒类电商运营纯营销。) Master OS — automated mastery of 侍酒师 / 葡萄酒 (Sommelier & Wine) — 葡萄酒鉴赏 + 侍酒服务的职业认知操作系统，从业者/侍酒师/学习者视角。覆盖: (a) 两大认证体系张力 — WSET (Wine & Spirit Education Trust, 英国, 知识+SAT 系统化品鉴方法, Diploma/L4 笔试导向) vs Court of Master Sommeliers (CMS, 美/英, 服务+盲品演绎法+理论三位一体, MS 头衔), 外加 Institute of Masters of Wine (MW, 学术研究+论文) 与 UC Davis 葡萄酒学/葡萄栽培学学院派; (b) 盲品 = 纯 tacit 校准技能 — 演绎品鉴网格 (deductive tasting: 看色/闻香/品味 → 结构线索 calculated structure → 推断品种/产区/年份/酒龄), WSET SAT vs CMS deductive grid 两套方法论; (c) 第一性张力 — codifiable 理论层 (产区/品种/酒法/风土/酿造/葡萄栽培) ⇄ tacit 校准层 (品鉴味觉记忆/盲品/侍酒服务), 这行的核心矛盾是「可背诵的知识」与「不可言传的味觉」之间; (d) 旧世界 vs 新世界框架 — 旧世界以风土/法定产区为组织原则 (AOC/DOCG/QbA 分级法), 新世界以品种为标签; 风土 (terroir) 是核心组织概念; (e) 侍酒服务/酒店层 — 餐厅 floor 的配餐 (food pairing)、醒酒/侍酒温度、酒单与酒窖管理、by-the-glass 与饮品项目经济学、盲品 service exam; (f) 葡萄酒商业层 — 三级分销体系 (美国 three-tier)、定价/配额 (allocation)、期酒 (en primeur)、投资酒 (Liv-ex) 与拍卖; (g) 智识/品味演进 — 帕克百分制 (Robert Parker / Wine Advocate 100-point) vs Jancis Robinson 20 分制散文派; 经典派 vs 现代派酿造; 自然酒/低干预 (natural/minimal-intervention) vs 传统技术派. 学派分歧: WSET 知识体系派 vs CMS 服务盲品派、旧世界风土派 vs 新世界品种/技术派、自然酒派 vs 传统派、百分制点评派 vs 散文叙述派、经典平衡派 vs 浓郁现代派. 不含: 家庭自酿 DIY 套件、纯调酒/鸡尾酒/烈酒、葡萄园重型农机工程、酒精成瘾/公共卫生政策、酒类电商运营纯营销。: top builders' mental models, tool stack, current workflows, jargon, and where to keep up. Trigger this skill when the user works on 侍酒师 / 葡萄酒 (Sommelier & Wine) — 葡萄酒鉴赏 + 侍酒服务的职业认知操作系统，从业者/侍酒师/学习者视角。覆盖: (a) 两大认证体系张力 — WSET (Wine & Spirit Education Trust, 英国, 知识+SAT 系统化品鉴方法, Diploma/L4 笔试导向) vs Court of Master Sommeliers (CMS, 美/英, 服务+盲品演绎法+理论三位一体, MS 头衔), 外加 Institute of Masters of Wine (MW, 学术研究+论文) 与 UC Davis 葡萄酒学/葡萄栽培学学院派; (b) 盲品 = 纯 tacit 校准技能 — 演绎品鉴网格 (deductive tasting: 看色/闻香/品味 → 结构线索 calculated structure → 推断品种/产区/年份/酒龄), WSET SAT vs CMS deductive grid 两套方法论; (c) 第一性张力 — codifiable 理论层 (产区/品种/酒法/风土/酿造/葡萄栽培) ⇄ tacit 校准层 (品鉴味觉记忆/盲品/侍酒服务), 这行的核心矛盾是「可背诵的知识」与「不可言传的味觉」之间; (d) 旧世界 vs 新世界框架 — 旧世界以风土/法定产区为组织原则 (AOC/DOCG/QbA 分级法), 新世界以品种为标签; 风土 (terroir) 是核心组织概念; (e) 侍酒服务/酒店层 — 餐厅 floor 的配餐 (food pairing)、醒酒/侍酒温度、酒单与酒窖管理、by-the-glass 与饮品项目经济学、盲品 service exam; (f) 葡萄酒商业层 — 三级分销体系 (美国 three-tier)、定价/配额 (allocation)、期酒 (en primeur)、投资酒 (Liv-ex) 与拍卖; (g) 智识/品味演进 — 帕克百分制 (Robert Parker / Wine Advocate 100-point) vs Jancis Robinson 20 分制散文派; 经典派 vs 现代派酿造; 自然酒/低干预 (natural/minimal-intervention) vs 传统技术派. 学派分歧: WSET 知识体系派 vs CMS 服务盲品派、旧世界风土派 vs 新世界品种/技术派、自然酒派 vs 传统派、百分制点评派 vs 散文叙述派、经典平衡派 vs 浓郁现代派. 不含: 家庭自酿 DIY 套件、纯调酒/鸡尾酒/烈酒、葡萄园重型农机工程、酒精成瘾/公共卫生政策、酒类电商运营纯营销。 problems and wants industry-grade thinking, tool selection, or workflow guidance. 触发词：「侍酒师」「sommelier」「葡萄酒」「wine」「盲品」
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Executes distribution calculations through partnership waterfall with preferred return, GP catch-up, and carried interest allocation. Use when calculating distributions, processing waterfall mechanics, or determining carry payments.
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Tactical guidance for composing Permission Set Groups: layering permission sets, applying Mute Permission Sets to subtract narrow capabilities, sequencing the recalculation lifecycle, deletion order, and assignment-vs-activation lifecycle. Triggers: 'PSG composition', 'mute permission set', 'PSG recalculation', 'cannot delete permission set in PSG', 'PSG explosion', 'expired PSG assignment'. NOT for the strategic profile-vs-PSG choice or migrating off profiles - use admin/permission-set-architecture. NOT for record-sharing design (OWD, role hierarchy, sharing rules) - use admin/sharing-and-visibility.
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Comprehensive calculus expert covering limits, derivatives, integrals, sequences, series, and multivariable calculus with rigorous proofs and practical applications
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Calculate statistical power and sample sizes for RCTs. Use when user mentions: power analysis, sample size calculation, minimum detectable effect, MDE, statistical power, effect size, clustering effects, design effect, ICC, intra-cluster correlation.
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This skill guides clinicians to assess bolus calculator settings when reviewing pump settings or verifying carb ratio and sensitivity factor during clinic visits. It evaluates insulin-to-carbohydrate ratio, insulin sensitivity factor, glucose targets, and active insulin time for embedded bolus calculators in CSII.
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