550 件 ・ 関連度順
概要と使いどころ
Domine SQL moderno com bancos de dados cloud-native, otimização OLTP/OLAP e técnicas avançadas de query. Especialista em tuning de performance, modelagem de dados e sistemas analíticos híbridos.
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Arquiteto de banco de dados especializado em design de camada de dados do zero, seleção de tecnologia, modelagem de schemas e arquiteturas de bancos de dados escaláveis.
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Criando visualizações de dados interativas usando d3.js. Esta habilidade deve ser usada ao criar gráficos customizados, diagramas de rede, visualizações geográficas ou qualquer visualização de dados complexa baseada em SVG que requeira controle fino sobre elementos visuais, transições ou interações. Use isto para visualizações personalizadas além das bibliotecas de gráficos padrão, seja em React, Vue, Svelte, JavaScript vanilla ou qualquer outro ambiente.
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Banco de dados de embeddings de código aberto para aplicações de IA. Armazene embeddings e metadados, realize buscas vetoriais e full-text, filtre por metadados. API simples com 4 funções. Escala de notebooks para clusters de produção. Use para busca semântica, aplicações RAG ou recuperação de documentos. Melhor para desenvolvimento local e projetos de código aberto.
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Analise dados do Google Analytics, revise métricas de desempenho do site, identifique padrões de tráfego e sugira melhorias orientadas por dados. Use quando o usuário pergunta sobre análise de dados, métricas de site, análise de tráfego, taxas de conversão, comportamento do usuário ou otimização de desempenho.
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Extraia dados estruturados de respostas de LLM com validação Pydantic, tente novamente automaticamente extrações que falharem, analise JSON complexo com segurança de tipo e transmita resultados parciais com Instructor - biblioteca de saída estruturada testada em batalha
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Sistema autônomo multi-agente para startups em Claude Code. Ativado com "Loki Mode". Orquestra 100+ agentes especializados em engenharia, QA, DevOps, segurança, dados/ML, operações comerciais, marketing, RH e sucesso do cliente. Vai de PRD para produto totalmente implantado e gerando receita com zero intervenção humana. Inclui ferramenta Task para despacho de subagentes, revisão de código paralela com 3 revisores especializados, triagem de problemas baseada em severidade, fila de tarefas distribuída com tratamento de dead letter, implantação automática em provedores de nuvem, testes A/B, loops de feedback de clientes, resposta a incidentes, circuit breakers e auto-recuperação. Gerencia limites de taxa via checkpoints de estado distribuído e retomada automática com backoff exponencial. Requer flag --dangerously-skip-permissions.
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Estenda janelas de contexto de modelos transformer usando RoPE, YaRN, ALiBi e técnicas de interpolação de posição. Use ao processar documentos longos (32k-128k+ tokens), estender modelos pré-treinados além dos limites de contexto originais ou implementar codificações posicionais eficientes. Cobre embeddings rotativos, vieses de atenção, métodos de interpolação e estratégias de extrapolação para LLMs.
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Use when the user asks to "codify how our founder sounds", "build a founder voice dossier", or "set our content pillars"; runs an 80%-extraction interview over the user's OWN posts, emails, and decks (never competitor scraping, never an invented persona) and produces the versioned voice record — a per-platform register map (incl. 小红书/微信公众号), banned phrases, per-context disclosure lines (the ECHO C2 upstream), a few-shot bank built exclusively from own posts, and 3-5 content pillars with Estimated %-allocations — submitted via memory/events/channels.ndjson for channel-registry to store as voice-dossier.md, the record every Craft-phase skill reads first. Not for the brand-level voice canon — use brand-language-codifier; not for audience/persona research — use audience-mapper. 声音档案/品牌语气/创始人语气/内容支柱/披露声明
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Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.
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Dose-response / concentration-response curve fitting — IC50, EC50, Hill slope, Emax/Emin efficacy, and relative potency from paired concentration vs response data (enzyme/cell assays, drug screening, agonist/antagonist pharmacology). Fits the 4-parameter logistic (Hill sigmoidal) model. Use when you have concentrations + responses and need a potency value, to compare two compounds' potency, or to judge curve quality. NOT for image-derived dose-response (use tooluniverse-image-analysis) and NOT for survival/regression (use tooluniverse-statistical-modeling).
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Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.
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Apple Remindersの予定付きToDoをMacから確認・追加・編集するスキル。リストの管理や完了・削除にも対応し、iPhoneやiPadで見るタスクを整理できます。
Build a graph-structured dossier on a seed entity via parallel fan-out + recursive expansion across web, memory, knowledge-graph, codebase, ADR index, and git intel
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Build threat actor profiles by collecting OSINT from vendor reports, paste sites, dark web forums, social media, and code repos, correlating indicators, mapping adversary infrastructure with tools like Maltego and SpiderFoot, and producing structured dossiers of motivations, capabilities, infrastructure, and TTPs. Use when performing attribution or building an adversary dossier from open-source intelligence.
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Deauthentication and disassociation attacks against 802.11 networks — targeted single-client deauth for handshake capture, broadcast deauth for DoS (with authorization), action-frame attacks bypassing 802.11w (PMF), beacon flooding, mdk4 / aireplay-ng tooling, and rate-limit / PMF-aware operation. Use to coerce client reconnection (handshake capture, evil-twin roaming), as targeted DoS, or to test PMF posture.
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Generate a therapeutic indication dossier. Covers the patient population, epidemiology, disease biology, standard of care, regulatory precedent, and landmark clinical trials.
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How to work in a Personal CRM project (the `entity-vault` starter pack, GBrain-compatible): a typed-entity vault of people, companies, meetings, and concepts, each a dossier with a rewritable summary plus an append-only timeline. Read when the project has these folders, OR when asked to capture notes about a person or company, log a meeting, prep for an upcoming meeting, or answer who someone is and what was last said. Carries the dossier convention and entity-extraction behaviors so that guidance does not live inside template bodies or folder descriptions. Complements the platform `open-knowledge` skill; does not replace it.
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List pending todos and select one to work on
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Analyzes CRISPR drug-modifier (chemogenomic) screens with drugZ (Colic et al. 2019 Genome Med), a bidirectional Z-score method that identifies synthetic-lethal sensitizing genes and resistance-conferring suppressor genes from vehicle vs drug comparisons. Covers vehicle-anchored design (not Day-0), the bidirectional Z math giving greater sensitivity to small-effect hits than MAGeCK / STARS / edgeR / RIGER on drug screens, per-gene sumZ and normZ, synth (sensitizer) vs supp (suppressor) FDR, multi-dose handling, integration with control sgRNAs, and comparison with MAGeCK MLE with dose covariate. Use when running a drug-modifier CRISPR screen, identifying sensitizing or resistance genes for a drug candidate, choosing drugZ vs MAGeCK MLE for chemogenomic analysis, troubleshooting low-effect drug screens where MAGeCK lacks sensitivity, or designing a drug-screen layout (vehicle vs drug arms).
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Apple Human Interface Guidelines expert across iOS, iPadOS, macOS, watchOS, tvOS, and visionOS. Use when designing or reviewing an Apple-platform app, auditing for HIG compliance, picking native components, or validating accessibility.
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Génération de sujets d'entraînement complets pour l'épreuve de NOTE DE SYNTHÈSE (5 heures, coefficient 3) de l'examen d'accès au CRFPA : choix du sujet, dossier documentaire de 16 à 20 documents assemblé à partir de sources réelles vérifiées (textes, jurisprudence, travaux parlementaires, doctrine) avec contrôle du verbatim, puis grille de notation au modèle de la Commission nationale (résumé de chaque document, problématique, thèmes cotés sur 20, plan). Livraison en deux fichiers .docx distincts, le sujet et la grille. Si l'utilisateur n'impose pas de sujet, en chercher un dans l'actualité juridique. Mode aveugle pour l'étudiant qui compose sans rien voir du corrigé. Déclencher dès que l'utilisateur demande un sujet de note de synthèse, un dossier documentaire, une note de synthèse blanche, un entraînement à l'épreuve de 5 heures du CRFPA ou de l'IEJ, ou une grille de note de synthèse. NE PAS déclencher pour les épreuves de 3 heures (sujet-crfpa-toutes-matieres) ni pour la correction de copies.
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Orientação completa sobre conformidade com regulamentações do Banco Central do Brasil: Resolução CMN nº 4.893/2021 (Política de Segurança Cibernética), Resolução BCB nº 85/2021 (GRSIC), Open Finance Brasil (Resoluções BCB nº 32/2020 e atualizações), e demais normas prudenciais do BACEN. Cobre elaboração e revisão de Política de Segurança Cibernética, Plano de Ação e Resposta a Incidentes (PARI), Gestão de Riscos de Serviços de Informação e Comunicação (GRSIC), consentimento e compartilhamento de dados no Open Finance, requisitos de API, gestão de terceiros (outsourcing) e sanções do BACEN. Triggers: Bacen, Banco Central, CMN 4.893, Resolução 4.893, segurança cibernética bancária, PARI, GRSIC, Open Finance, Open Banking, compartilhamento de dados financeiros, consentimento Open Finance, API financeira, outsourcing bancário, risco cibernético, incidente cibernético banco, LGPD financeira, fintech compliance, instituição financeira, DICT, Pix segurança.
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Expert knowledge for Azure Security development including best practices, decision making, security, configuration, integrations & coding patterns, and deployment. Use when configuring Azure antimalware, container SBOM/signing, CMK encryption, AKS/VM hardening, or Key Vault keys, and other Azure Security related development tasks. Not for Azure Defender For Cloud (use azure-defender-for-cloud), Azure Information Protection (use azure-information-protection), Azure DDoS Protection (use azure-ddos-protection), Azure Web Application Firewall (use azure-web-application-firewall).
日本語の概要は準備中です。原文の説明を表示しています。