本文へ移動
cccskills

「top-level」の検索結果

53 件 ・ 関連度順

概要と使いどころ

Identifies differential m6A methylation between conditions from MeRIP-seq paired IP/input data using exomePeak2 with `bam_ip` + `bam_input` (control arm) and `bam_treated_ip` + `bam_treated_input` (treatment arm) for integrated GC-bias-aware differential calling (Liu 2022 *NAR Genom Bioinform* 4:lqac046), QNB beta-binomial test (Liu 2017 *BMC Bioinformatics* 18:387), MeTDiff HMM-based differential bundled with MeTPeak, RADAR (Zhang 2019 *Genome Biol* 20:294) with its `filterBins -> diffIP -> reportResult` workflow, and the defensible paired-symmetric case of edgeR / DESeq2 on featureCounts-on-peaks matrices when batch / lot covariates need explicit fixed-effect handling (exomePeak2's top-level API does NOT accept arbitrary covariates). Covers paired vs unpaired vs interaction designs, batch confounding (antibody lot, RNA prep, sequencing run) and the per-lot meta-analysis strategy when exomePeak2 is the primary caller, the stoichiometry-vs-expression-vs-IP-efficiency confound that all MeRIP differential methods inherit, normalisation choice (size factor on IP, on input, on per-sample IP/input ratio), the McIntyre 2020 reproducibility caveat, effect-size filtering as a guardrail against under-powered N=2 designs, and orthogonal-validation routes for absolute stoichiometry (GLORI / SAC-seq / m6Anet `mod_ratio`). Use when comparing m6A levels across two or more conditions, choosing between exomePeak2 / QNB / RADAR / MeTDiff for a given design, handling batch confounding when exomePeak2's API is too rigid, normalising against input properly, distinguishing real hyper- / hypo-methylation from expression-level shifts, applying effect-size thresholds, interpreting volcano plots of differential peaks, or planning a follow-up orthogonal stoichiometry validation.

日本語の概要は準備中です。原文の説明を表示しています。

peacezha/HPClaw32026年10月11日 更新

Monitor Power Automate flow health, track failure rates, and inventory tenant assets using the FlowStudio MCP cached store. The live API only returns top-level run status. Store tools surface aggregated stats, per-run failure details with remediation hints, maker activity, and Power Apps inventory — all from a fast cache with no rate-limit pressure on the PA API. Load this skill when asked to: check flow health, find failing flows, get failure rates, review error trends, list all flows with monitoring enabled, check who built a flow, find inactive makers, inventory Power Apps, see environment or connection counts, get a flow summary, or any tenant-wide health overview. Requires a FlowStudio for Teams or MCP Pro+ subscription — see https://mcp.flowstudio.app

日本語の概要は準備中です。原文の説明を表示しています。

jcasnellie69/homelab-config22026年10月12日 更新

Give your AI agent the same visibility you have in the Power Automate portal — plus a bit more. The Graph API only returns top-level run status. Flow Studio MCP exposes action-level inputs, outputs, loop iterations, and nested child flow failures. Use when asked to: list flows, read a flow definition, check run history, inspect action outputs, resubmit a run, cancel a running flow, view connections, get a trigger URL, validate a definition, monitor flow health, or any task that requires talking to the Power Automate API through an MCP tool. Also use for Power Platform environment discovery and connection management. Requires a FlowStudio MCP subscription or compatible server — see https://mcp.flowstudio.app

日本語の概要は準備中です。原文の説明を表示しています。

jcasnellie69/homelab-config22026年10月12日 更新

Debug failing Power Automate cloud flows using the FlowStudio MCP server. The Graph API only shows top-level status codes. This skill gives your agent action-level inputs and outputs to find the actual root cause. Load this skill when asked to: debug a flow, investigate a failed run, why is this flow failing, inspect action outputs, find the root cause of a flow error, fix a broken Power Automate flow, diagnose a timeout, trace a DynamicOperationRequestFailure, check connector auth errors, read error details from a run, or troubleshoot expression failures. Requires a FlowStudio MCP subscription — see https://mcp.flowstudio.app

日本語の概要は準備中です。原文の説明を表示しています。

jcasnellie69/homelab-config22026年10月12日 更新

Refines raw ideas through structured divergent and convergent thinking for ordinary non-command brainstorming, idea shaping, options comparison, and explicit IDEATE deepening routed by `aili-delivery-flow`; do not use as the top-level `/ideate` command owner or for existing-plan stress-test, review, or completion-claim checks.

日本語の概要は準備中です。原文の説明を表示しています。

Rosetears520/aili-workflows22026年9月27日 更新