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Orchestrator + builder for distinctive, production-grade frontends that don't look AI-generated. Derives stack and design context from product-soul/PRD/specs, then runs the anti-slop chain — explore distinct directions, lock a DESIGN.md system, build from golden examples with mandatory polish + every interactive/empty/loading/error state, then review. Load when the user asks to build a UI, design a frontend, build a landing page or dashboard or web app, beautify or redesign a page, make a UI look premium/playful/editorial, says "build me a frontend", "make this not look AI-generated", "design this interface", "give this real polish", or "frontend design". Routes to design-direction, design-system, design-review.

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Modern Angular UI patterns for loading states, error handling, and data display. Use when building UI components, handling async data, or managing component states.

日本語の概要は準備中です。原文の説明を表示しています。

Loads, converts, and manipulates Hi-C contact matrices in cooler format (.cool/.mcool/.scool) and Juicer .hic, using cooler (Python + CLI), hic2cool, and hictk. Covers the single-resolution mcool URI (file.mcool::/resolutions/<bp>), the load-bearing divisive-vs-multiplicative weight-naming rule (KR/VC/VC_SQRT auto-divisive vs cooler's multiplicative weight), what survives .hic<->.cool conversion (FRAG matrices and norm vectors do not), raw-vs-balanced coarsening, the .pairs upper-triangle/chromsize-order contract, and chrom-naming/bin-table provenance. Use when loading a cooler, converting .hic to .mcool, selecting a resolution, building a cooler from pairs or a matrix, coarsening/zoomifying, importing Juicer norm vectors, or debugging all-NaN balanced matrices and chr1-vs-1 empty fetches.

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Reads, inspects, and writes Flow Cytometry Standard (FCS) files from conventional, spectral, and mass cytometry (CyTOF), and parses FlowJo/Cytobank/Diva workspaces. Covers FCS 2.0/3.0/3.1/3.2 internals ($PnE linear-vs-log, $DATATYPE, $SPILLOVER vs SPILL vs $COMP, $TIMESTEP), channel/parameter metadata, the silent linearize/truncate defaults, and R (flowCore, flowWorkspace, CytoML) plus Python (FlowKit, readfcs) readers. Use when loading flow or mass cytometry data, mapping detector channels to antibodies, extracting the event matrix, choosing a reader, or bridging FCS to the scanpy/AnnData ecosystem before preprocessing.

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Query and download from NCBI Gene Expression Omnibus (GEO) and EMBL-EBI's BioStudies/ArrayExpress mirror. Use when finding expression datasets, navigating SuperSeries vs SubSeries, choosing between series-matrix (submitter-normalized) and raw supplementary files, downloading via GEOparse (Python) or GEOquery (R/Bioconductor), linking GEO to SRA for raw reads, or distinguishing GSE/GSM/GPL/GDS record types. Encodes the SuperSeries trap, the series-matrix normalization-trust caveat, GEOmetadb deprecation, ArrayExpress migration to BioStudies, and processed-vs-raw decision matrix.

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Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions), hyperparameter sensitivity, and the well-documented limits of 2D embeddings. Covers PCA biplot/scree/loadings, t-SNE PCA initialization (Kobak-Berens 2019), UMAP n_neighbors/min_dist trade-offs, and the Chari-Pachter 2023 critique. Use when visualizing high-dimensional data — bulk PCA, single-cell embeddings, multi-omics integration projections.

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Retrieve records from NCBI databases using Biopython Bio.Entrez (EFetch, ESummary). Use when downloading sequences, fetching GenBank/GenPept records, getting document summaries, parsing nested XML, navigating GI deprecation, choosing between rettype+retmode combinations, and parsing into Biopython SeqRecord/SwissProt objects. Covers nucleotide, protein, gene, pubmed, sra, gds, taxonomy, snp, clinvar.

日本語の概要は準備中です。原文の説明を表示しています。

Build local BLAST databases and run searches using NCBI BLAST+ command-line tools. Use when running >50 queries, building custom databases with -parse_seqids and -taxid, downloading prebuilt NCBI databases via update_blastdb.pl, choosing -task variants (megablast/dc-megablast/blastn/blastn-short), tuning soft/hard masking, scaling threads, or extracting hits with blastdbcmd. Encodes BLAST v5 vs v4 database format, taxonomy filtering, makeblastdb pitfalls.

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Reads, writes, and converts molecular file formats (SMILES, InChI, SDF V2000/V3000, MOL2, PDB, MMTF) using RDKit and Open Babel with rigorous handling of aromaticity perception, stereochemistry, implicit/explicit hydrogens, kekulization, and salt/fragment separation. Use when loading chemical libraries, debugging parse failures, or preparing molecules for downstream standardization, descriptor calculation, or docking.

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Turn a large dataset (an existing oversized Coval test set, an export of past conversations, or a CSV/JSON of cases) into a small, high-signal Coval test set by removing duplicates, identifying unique scenarios, and selecting a representative, failure-weighted subset — then bulk-loading it with no row cap. Use when the user says "I have thousands of cases", "dedupe my test set", "my test set is too big", "turn this dataset into a test set", "pick representative scenarios", or "my CSV import only kept 10 / uploaded everything".

日本語の概要は準備中です。原文の説明を表示しています。

Image optimization analysis for SEO and performance. Checks alt text, file sizes, formats, responsive images, lazy loading, CLS prevention, image SERP rankings (via DataForSEO), and image file optimization (WebP/AVIF conversion, IPTC/XMP metadata injection). Use when user says "image optimization", "alt text", "image SEO", "image size", "image audit", "optimize images", "image metadata", "image SERP", "convert to webp", or "image file optimize".

日本語の概要は準備中です。原文の説明を表示しています。

Refine UI posture — improve an existing screen without reinventing it. Use when the current page is roughly right but needs polish (hierarchy, spacing, labels, loading/empty/error states, mobile breakage), or when consistency with the rest of the app matters more than novelty.

日本語の概要は準備中です。原文の説明を表示しています。

next/dynamic code splitting and build-graph cost; first stop for build failures. Use before lazy-loading or deferring a heavy component, adding a dynamic import, React.lazy, or ssr: false; on 'window is not defined' or a hydration mismatch; shrinking the bundle; or on 'build failed', OOM, SIGKILL, a slower build, or 'Collecting page data'.

日本語の概要は準備中です。原文の説明を表示しています。

Diagnoses and fixes UI performance across loading speed, rendering, animations, images, and bundle size. Use when the user mentions slow, laggy, janky, performance, bundle size, load time, or wants a faster, smoother experience.

日本語の概要は準備中です。原文の説明を表示しています。

Parse and validate project specifications. Use when loading YAML/JSON specs, validating spec structure, extracting requirements, or converting between spec formats.

日本語の概要は準備中です。原文の説明を表示しています。

When the user needs to set up multiple academic courses in a learning management system (Canvas/LMS) from structured data sources. This skill automates the entire workflow extracting course schedules from emails/attachments, matching instructors from CSV files, creating courses, enrolling teachers, publishing announcements with class details, uploading syllabi, enabling resource sharing for instructors teaching multiple courses, and publishing all courses. Triggers include course schedule setup, Canvas/LMS administration, academic term preparation, instructor assignment, syllabus distribution, and multi-course management.

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When the user requests information about academic benchmarks, datasets, or research papers, particularly in machine learning, deep learning, or logical reasoning domains. This skill enables systematic research of academic benchmarks by searching web sources, downloading and analyzing arXiv papers, extracting key metadata (number of tasks, training availability, difficulty levels), and compiling comparative summaries. It triggers on requests involving dataset comparisons, benchmark analysis, or academic paper research for table creation.

日本語の概要は準備中です。原文の説明を表示しています。

Download and manage abqpy API documentation. Use when user asks about API documentation, API reference, or downloading Abaqus docs.

日本語の概要は準備中です。原文の説明を表示しています。

Swift 6.2 Approachable Concurrency — single-threaded by default, @concurrent for explicit background offloading, isolated conformances for main actor types.

日本語の概要は準備中です。原文の説明を表示しています。

Modern Angular UI patterns for loading states, error handling, and data display. Use when building UI components, handling async data, or managing component states.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when building analytics dashboards with nuxt-ui-tools as a package consumer. Covers schema and view functions (defineDashboardSchema, defineDashboardView) that take their context as typed params, useDashboard with a getter that rebuilds on input change, typed injection (useDashboardView, injectDashboard, InferDashboard, InferDashboardView), filters declared inline with the f builder and synced with the URL, memory, or an external store (one value per key across views), headless filters, filter controls and the shipped UI (UiDashboardPage, UiDashboardFilters, UiDashboardFilter, UiDashboardViewTabs) with slot overrides, remote paginated pickers and remoteTableOptions, staged queries (essential / background / deferred) with select and dependent requires, lazy enabled conditions on views, queries, and filters (blocks of disabled queries hidden, grids closing up), derived values, views (tabs), query-scoped filters, number formats (presets, Intl options, useDashboardFormat), and the dashboard blocks (stats with trends, goals, and comparisons, stat groups, gauges, unovis charts with highlights, value labels, and totals, lists with progress rings, bars, funnel, alerts, activity feeds, sortable tables, custom widgets) with their automatic loading, error, empty, and refresh states, card menus, header and footer actions, row actions, drill-down and selected state, card tabs, split cards, comparison periods, auto-refresh, and data freshness.

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Use this skill when building or debugging table usage with nuxt-ui-tools as a package consumer. Covers defineTableSchema, useTable, DataList, granular composition, columns, filters, sorting, offset or cursor loading, layouts, actions, selection, context, and URL state with concrete examples.

日本語の概要は準備中です。原文の説明を表示しています。

Expert guidance for Fully Sharded Data Parallel training with PyTorch FSDP - parameter sharding, mixed precision, CPU offloading, FSDP2

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Complete knowledge domain for Firecrawl v2 API - web scraping and crawling that converts websites into LLM-ready markdown or structured data. Use when: scraping websites, crawling entire sites, extracting web content, converting HTML to markdown, building web scrapers, handling dynamic JavaScript content, bypassing anti-bot protection, extracting structured data from web pages, or when encountering "content not loading", "JavaScript rendering issues", or "blocked by bot detection". Keywords: firecrawl, firecrawl api, web scraping, web crawler, scrape website, crawl website, extract content, html to markdown, site crawler, content extraction, web automation, firecrawl-py, firecrawl-js, llm ready data, structured data extraction, bot bypass, javascript rendering, scraping api, crawling api, map urls, batch scraping

日本語の概要は準備中です。原文の説明を表示しています。