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Idiomatic Go concurrency - sync primitives, channel semantics, the select statement, and the standard channel patterns (cancellation/done-channel, fan-out/fan-in, pipeline, or-done, context, worker-pool). Use when writing or reviewing Go that spawns goroutines, shares state, or coordinates over channels, even if the user never says "concurrency" - e.g. data races, deadlocks, goroutine leaks, sync/context/select usage, or "make this parallel". Distilled from luk4z7/go-concurrency-guide.

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Automate Cloudinary media management including folder organization, upload presets, asset lookup, transformations, and usage monitoring through natural language commands

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Automate Anthropic Admin tasks via Rube MCP (Composio): API keys, usage, workspaces, and organization management. Always search tools first for current schemas.

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Complete guide to using and extending Hermes Agent — CLI usage, setup, configuration, spawning additional agents, gateway platforms, skills, voice, tools, profiles, and a concise contributor reference. Load this skill when helping users configure Hermes, troubleshoot issues, spawn agent instances, or make code contributions.

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Detect horizontal gene transfer (HGT / LGT) using compositional methods (GC%, codon usage, tetranucleotide z-scores via SIGI-HMM, AlienHunter, IslandViewer 4, IslandPath-DIMOB), phylogenetic-incongruence methods (AvP, HGTphyloDetect, ALE / GeneRax / AleRax reconciliation, RANGER-DTL), and BLAST-distribution methods (HGTector v2, DarkHorse, Alien Index). Use when screening prokaryote genomes for genomic islands and HGT events, distinguishing HGT from incomplete lineage sorting / differential gene loss / hybridization, mapping donor lineages via phylogenetic placement, separating eukaryotic HGT from contamination, ruling out gBGC as a false signal, or quantifying DTL rates with ALE/GeneRax on bacterial trees.

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Analyzes differential transcript usage (DTU) and isoform switches with functional consequence prediction (NMD via 50nt rule, ORF disruption, protein domain loss/gain, signal peptide changes, IDR alterations, coding-potential shifts). Tools include IsoformSwitchAnalyzeR v2 (auto-selects satuRn for >5 reps else DEXSeq), the manual DRIMSeq -> DEXSeq/satuRn -> stageR DTU pipeline, and fishpond/swish for inferential-uncertainty-aware DTE. Distinguishes DTU from DGE and DTE; integrates external annotators (CPC2, Pfam, SignalP, IUPred2A or DeepTMHMM). Use when investigating how splicing differences alter protein function or trigger NMD-mediated degradation.

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Quantifies alternative splicing as PSI (percent spliced in) from RNA-seq using rMATS-turbo (BAM-based event), SUPPA2 (TPM-based event), MAJIQ V3 (LSV-based Bayesian), leafcutter (annotation-free intron clusters), VAST-TOOLS (cross-species with microexon support), Shiba (junction-imbalance-corrected, 2025 SOTA at low coverage), or IRFinder-S (intron retention coverage-aware). Distinguishes the five canonical event classes (SE, A5SS, A3SS, MXE, RI), special classes (microexons, exitrons, AFE/ALE), intron retention subtypes (canonical RI vs detained introns), and applies effective-length normalization. Use when measuring splice-site usage or isoform inclusion ratios from short-read RNA-seq.

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Analyzes alternative splicing at single-cell resolution. The first decision is library chemistry — 10X 3' is fundamentally limited (RT primes from poly-A, R2 falls in 3' UTR, <0.1 junction read per cell per AS event). Plate-based full-length methods (Smart-seq3, FLASH-seq, VASA-seq, STORM-seq) and single-cell long-read (MAS-Iso-seq, scISOr-Seq2) are the chemistries that give per-cell isoform structure. Tools include MARVEL (R, Smart-seq integrated), BRIE2 (Bayesian PSI with regulatory features and ELBO_gain test), scQuint (junction-cluster, plate-based; not for 10X), SpliZ (annotation-free Z-score), Psix (graph-smoothness regulated AS), and Sierra (alternative polyadenylation, often confused with AS). Use when analyzing isoform usage in scRNA-seq, identifying cell-type-specific splicing, or determining whether scRNA-seq chemistry supports splicing analysis at all.

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Build or improve a Coval dashboard with metric visualizations backed by real data. Creates new dashboards from scratch or rebuilds existing ones by analyzing usage patterns, metric frequency, and data density. Use when user says "create a dashboard", "build a dashboard", "improve my dashboard", "add widgets", "visualize my metrics", "make a performance dashboard", or "dashboard for my runs".

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Recommend, create, preview, and attach Coval trace-based metrics from OpenTelemetry spans. Use when a user has Coval traces and wants custom trace metrics, trace-aware LLM judge metrics with include_traces, latency, token usage, provider failures, tool behavior, vertical-specific workflow signals, or production monitoring based on trace attributes.

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Find and identify the CCSPlayerPawn_SnapViewAngles function in CS2 server binary using IDA Pro MCP. Use this skill when reverse engineering CS2 server.dll or libserver.so to locate the non-virtual SnapViewAngles method, anchored on the "setang" console-command usage string and its non-teleport call branch. Emits a unique IDA-style byte signature and a func YAML. Trigger: CCSPlayerPawn_SnapViewAngles, SnapViewAngles

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Manages shadcn components and projects — adding, searching, fixing, debugging, styling, and composing UI. Provides project context, component docs, and usage examples. Applies when working with shadcn/ui, component registries, presets, --preset codes, or any project with a components.json file. Also triggers for "shadcn init", "create an app with --preset", or "switch to --preset".

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Generates README.md files for PHP projects. Creates structured documentation with badges, installation, usage, and examples.

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Generates PSR-3 Logger implementation for PHP 8.5. Creates LoggerInterface implementations with log levels, context interpolation, and LoggerAwareTrait usage. Includes unit tests.

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Plan, validate, and use 1Password CLI setup for secret injection and auth. Use when tasks need 1Password CLI usage, secret references, op run/read/inject, or provisioning secrets via env vars/.env files and scripts.

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Java coding standards for Spring Boot services: naming, immutability, Optional usage, streams, exceptions, generics, and project layout.

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Cost optimization patterns for LLM API usage — model routing by task complexity, budget tracking, retry logic, and prompt caching.

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Build AI phone agents with AgentPhone API. Use when the user wants to make phone calls, send/receive SMS, manage phone numbers, create voice agents, set up webhooks, or check usage — anything related to telephony, phone numbers, or voice AI.

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Use this skill for internal Vue reactivity and state-model work in the nuxt-ui-tools repository. Covers lean reactivity, query-state integration, when to use computed vs watch vs shallowRef, VueUse usage, and how to simplify over-layered state models.

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Use this skill when working with the nuxt-ui-tools package as a consumer or integrator. It provides the current package overview and routes to table, form, dashboard, file preview, query-state, shared responsive helpers, remote option loaders, and i18n usage.

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Use this skill when building or debugging table usage with nuxt-ui-tools as a package consumer. Covers defineTableSchema, useTable, DataList, granular composition, columns, filters, sorting, offset or cursor loading, layouts, actions, selection, context, and URL state with concrete examples.

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Use this skill for shared nuxt-ui-tools runtime usage, including responsive values and reusable remote option loaders for dashboard filters, table filters, and form fields.

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Complete guide to using and extending Hermes Agent — CLI usage, setup, configuration, spawning additional agents, gateway platforms, skills, voice, tools, profiles, and a concise contributor reference. Load this skill when helping users configure Hermes, troubleshoot issues, spawn agent instances, or make code contributions.

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Optimize AgentDB performance with quantization (4-32x memory reduction), HNSW indexing (150x faster search), caching, and batch operations. Use when optimizing memory usage, improving search speed, or scaling to millions of vectors.

日本語の概要は準備中です。原文の説明を表示しています。