「separation」の検索結果

Reads, writes, and converts molecular file formats (SMILES, InChI, SDF V2000/V3000, MOL2, PDB, MMTF) using RDKit and Open Babel with rigorous handling of aromaticity perception, stereochemistry, implicit/explicit hydrogens, kekulization, and salt/fragment separation. Use when loading chemical libraries, debugging parse failures, or preparing molecules for downstream standardization, descriptor calculation, or docking.

日本語の概要は準備中です。原文の説明を表示しています。

5W1H Decision Framework Tool. Use for: (1) Systematic decision-making before creating todos, (2) Preventing duplicate implementation, (3) Detecting avoidance behavior, (4) Ensuring agile refactor compliance with executor/dispatcher separation

日本語の概要は準備中です。原文の説明を表示しています。

Scaffolds a complete .NET solution following Clean Architecture principles with proper layer separation (API, Application, Domain, Infrastructure). Creates project structure, dependency injection setup, and cross-cutting concerns configuration.

日本語の概要は準備中です。原文の説明を表示しています。

リファクタリング（構造変更）と機能変更（behavior change）が同一 diff に混在していないかを識別し、structural change に対する external behavior preservation の証拠（テスト・型・静的解析）が揃っているかを diff-time で確認する。証拠不足のときは Characterization Test 追加を促すか question とする。DTO/公開 API の破壊的変更検出は api-compatibility、完了主張の反証や抽出リファクタの性能特性退行は refactor-claim-audit、新知識の命名・責務・境界への反映は knowledge-to-code-alignment、投機的抽象化・スコープ逸脱は altitude-generalization / fix-scope-integrity へ委譲する

Iteratively detects and auto-fixes technical debt in a codebase using three quality criteria from debt-analysis references: conditional branch simplification, encapsulation, and separation of concerns. Applies fixes directly to code, runs existing tests to verify no regressions, re-analyzes, and loops until all high-severity issues are resolved or max iterations (5) reached. Use this skill when you want to automatically improve code quality with real code changes, reduce technical debt systematically, or clean up code to meet quality standards. Trigger on phrases like "fix technical debt", "clean up code quality", "refactor and fix issues", "improve code quality automatically", "apply debt fixes", "fix code problems", "eliminate debt".

日本語の概要は準備中です。原文の説明を表示しています。

Architect scalable backend services using layered architecture, dependency injection, middleware patterns, service classes, and separation of concerns. Use when building API services, implementing business logic layers, creating service classes, setting up middleware chains, implementing dependency injection, designing controller-service-repository patterns, handling cross-cutting concerns, creating domain models, implementing CQRS patterns, or establishing backend architecture standards.

日本語の概要は準備中です。原文の説明を表示しています。

Reads, writes, and converts molecular file formats (SMILES, InChI, SDF V2000/V3000, MOL2, PDB, MMTF) using RDKit and Open Babel with rigorous handling of aromaticity perception, stereochemistry, implicit/explicit hydrogens, kekulization, and salt/fragment separation. Use when loading chemical libraries, debugging parse failures, or preparing molecules for downstream standardization, descriptor calculation, or docking.

日本語の概要は準備中です。原文の説明を表示しています。

Performs logistic regression for clinical trial outcomes (binary, ordinal, multinomial) with marginal-vs-conditional estimand reporting per FDA 2023 covariate adjustment guidance, g-computation/standardisation for marginal effects, modified Poisson for RR, Brant test for proportional odds, Firth penalty for separation, and Hauck-Donner detection. Use when modeling binary or ordinal endpoints in confirmatory or exploratory clinical trials.

日本語の概要は準備中です。原文の説明を表示しています。

Validate one Coval judge against independent human labels, with grouped development/test separation, class-specific errors and uncertainty. Use for trust claims or calibration; without real labels, prepare review rather than inventing ground truth.

日本語の概要は準備中です。原文の説明を表示しています。

5W1H Decision Framework Tool. Use for: (1) Systematic decision-making before creating todos, (2) Preventing duplicate implementation, (3) Detecting avoidance behavior, (4) Ensuring agile refactor compliance with executor/dispatcher separation

日本語の概要は準備中です。原文の説明を表示しています。

Cache expensive file processing results using SHA-256 content hashes — path-independent, auto-invalidating, with service layer separation.

日本語の概要は準備中です。原文の説明を表示しています。

Domain-Driven Design architecture for claude-flow v3. Implements modular, bounded context architecture with clean separation of concerns and microkernel pattern.

日本語の概要は準備中です。原文の説明を表示しています。

Structures CLI app layers. Command/handler/service separation, clig.dev principles, exit codes.

日本語の概要は準備中です。原文の説明を表示しています。

Implement Microsoft's Enhanced Security Admin Environment (ESAE) tiered administration model for Active Directory. Covers Tier 0/1/2 separation, privileged access workstations (PAWs), administrative f

日本語の概要は準備中です。原文の説明を表示しています。

Refactors route handlers into service layer with clean boundaries, dependency injection, testability, and separation of concerns. Provides service interfaces, folder structure, testing strategy, and migration plan. Use when refactoring "fat controllers", "business logic", "service layer", or "architecture cleanup".

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Penetration test and red team report writing methodology. Covers executive summary structuring (risk-led narrative for non-technical readers), technical finding format (title, severity, affected scope, narrative, reproduction steps, impact, remediation, references), CVSS v3.1 / v4.0 scoring with vector justification, OWASP risk rating, evidence hygiene (redacting credentials, hashing client data, time-stamping every action), screenshot and PoC artifact management, finding chain narratives, scope/limitations/assumptions documentation, retest evidence and remediation tracking, deliverable formats (PDF, DOCX, HTML, JSON for SIEM ingestion), client-customer-deliverable separation, and common report mistakes (over-CVSSing, undermining the triager, missing the 'so what'). Use at the end of an engagement when authoring a deliverable, when restructuring a draft for executive readability, or when establishing a reusable report template for a consulting practice.

日本語の概要は準備中です。原文の説明を表示しています。