「tool calling」の検索結果

Local LLM inference with the Ollama JavaScript client -- chat, streaming, tool calling, vision, embeddings, structured output, model management, and OpenAI-compatible endpoint

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Execute ENCODE DNase-seq pipeline from FASTQ to hotspots and footprints. Child of pipeline-guide. Provides Nextflow execution with Docker and cloud deployment. Use when processing DNase-seq data, calling DNase hypersensitive sites, performing footprinting analysis. Trigger on: DNase-seq pipeline, DNase hypersensitive, DHS, Hotspot2, footprinting, DNase I, chromatin accessibility DNase.

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Guides the usage of Gemini Interactions API on Gemini Enterprise Agent Platform. Use when the user wants to use the stateful, server-managed Interactions API for multi-turn conversations, background execution, streaming, structured output, and function calling on the Agent Platform.

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Connects to and performs inference with Google Cloud Agent Platform GenAI models, including First-Party Gemini models and Third-Party OpenMaaS models (Llama, DeepSeek, Qwen, etc.). Use when asked to perform inference, ask a model a question, run a test prompt, execute chat completions, or generate code for calling Gemini or OpenMaaS models, authenticate with GenAI SDK, OpenAI SDK, or legacy Agent Platform SDK, configure base URLs and global/regional endpoints, or troubleshoot 429 Resource Exhausted (DSQ), 400 User Validation, or 404 Not Found errors. Don't use for deploying models to endpoints or for running model evaluations.

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Apple FoundationModels framework for on-device LLM — text generation, guided generation with @Generable, tool calling, and snapshot streaming in iOS 26+.

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Build agents on OpenAI's platform patterns — assistants-style threads, function calling, structured outputs, and multi-step tool workflows. Use when working with OpenAI models as the agent engine.

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Detects acquired antimicrobial-resistance determinants and chromosomal point-mutation resistance in bacterial assemblies using AMRFinderPlus, ResFinder 4.0 (acquired + PointFinder), CARD-RGI, abritAMR, staramr, and species-specific callers (TB-Profiler, Mykrobe). Harmonises cross-tool output via hAMRonization, contextualises determinants with mobile-genetic-element annotation (MOB-suite, PlasmidFinder, MobileElementFinder, ICEberg), predicts phenotype against EUCAST or CLSI breakpoints, and translates calls into WHO GLASS reporting categories. Use when screening clinical or surveillance isolates for AMR, distinguishing acquired vs intrinsic vs point-mutation resistance, calling rpoB / katG / pncA / gyrA / mgrB mutations, reconciling AMRFinderPlus vs RGI vs ResFinder disagreement, contextualising carbapenemases or mcr alleles on plasmids, predicting susceptibility from genotype against the WHO Mtb 2nd-edition catalogue, or building a hAMRonized multi-lab AMR surveillance pipeline.

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Mark and remove PCR/optical duplicates using samtools fixmate and markdup. Use when preparing alignments for variant calling or when duplicate reads would bias analysis.

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Sort alignment files by coordinate or read name using samtools and pysam. Use when preparing BAM files for indexing, variant calling, or paired-end analysis.

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Find the papers that answer a research query in Firecrawl's research paper index — a corpus of paper abstracts whose largest share is biomedical and life-science literature (PubMed, bioRxiv, medRxiv), alongside arXiv preprints in CS, physics, and math — using semantic search, semantic and structural expansion, and in-body verification. Use this skill for literature-finding and paper-retrieval tasks of any kind, including clinical, biomedical, drug, gene, disease, and other life-science questions, whether the answer is a single paper or a full multi-paper set. The index is reached only through the `firecrawl_research_*` MCP tools or the `firecrawl research` CLI subcommands. Calling `firecrawl_search` with its `categories` option set to `["research"]` is a different feature — it filters ordinary web search to research-affiliated websites (the list includes PubMed, bioRxiv, medRxiv, arXiv, and publisher sites) and returns page results from them, without querying the paper records in this index.

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Operate the WeChat Official Account AI-application workflow for articles, weekly digests, rich formatting, draft-box updates, and local handoff. Use for Agents, MCP, Skills, tool calling, workflows, and open-source AI updates; exclude Xiaohongshu and Xianyu.

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Azure AI Agents Persistent SDK for .NET. Low-level SDK for creating and managing AI agents with threads, messages, runs, and tools. Use for agent CRUD, conversation threads, streaming responses, function calling, file search, and code interpreter. Triggers: "PersistentAgentsClient", "persistent a...

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Run 150+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation. Models: FLUX, Veo, Gemini, Grok, Claude, Seedance, OmniHuman, Tavily, Exa, OpenRouter, and many more. Use when running AI apps, generating images/videos, calling LLMs, web search...

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**MANDATORY prerequisite** — you MUST invoke this skill BEFORE every `create_new_file` tool call. NEVER call `create_new_file` directly without loading this skill first. Trigger whenever the user wants a new blank Figma file — a new design, FigJam, or Slides file — or when you need a fresh file before calling `use_figma`. Usage — /figma-create-new-file [editorType] [fileName] (e.g. /figma-create-new-file figjam My Whiteboard, /figma-create-new-file slides Q3 Review)

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**MANDATORY prerequisite** — you MUST invoke this skill BEFORE calling the `get_design_context` Figma MCP tool. You MUST trigger this skill whenever the user wants to implement, build, port, or code up a Figma design as code. Example prompts (not exhaustive) are 'implement this Figma design', 'build this screen from Figma', 'turn this Figma into code', 'design to code'. This skill provides critical instructions and steps to the agent on how to correctly implement Figma designs in code and must NOT be skipped.

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Expert in the Vercel AI SDK. Covers Core API (generateText, streamText), UI hooks (useChat, useCompletion), tool calling, and streaming UI components with React and Next.js.

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Vercel AI SDK expert guidance. Use when building AI-powered features — chat interfaces, text generation, structured output, tool calling, agents, MCP integration, streaming, embeddings, reranking, image generation, or working with any LLM provider.

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End-to-end neoantigen discovery from somatic variants to ranked vaccine candidates. Integrates HLA typing, MHC binding prediction, pVACtools neoantigen calling, and immunogenicity scoring. Use when identifying tumor neoantigens for personalized vaccine design or checkpoint biomarkers.

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The complete rules for writing or editing a shape's component (kind component). Use when creating, editing, patching or fixing a kind component, calling any kindcomp_* tool, or when a shape renders empty, broken, cropped, cramped or ugly.

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Detects TAD boundaries from balanced Hi-C contact matrices via the diamond-window insulation score (cooltools insulation) and HiCExplorer hicFindTADs, returning a continuous log2 insulation track, valley-prominence boundary_strength, and Li/Otsu-thresholded is_boundary flags across a list of window sizes. Covers the multi-scale window sweep (sub-TAD to compartment-domain), why the boundary is reproducible but the domain partition is not, cross-condition comparison via differential SCORE not differential partition, and the insulation-vs-compartment orthogonality. Use when calling TADs or domain boundaries, computing insulation scores, choosing a window size, ranking boundary strength, comparing boundaries across conditions, or annotating CTCF-backed boundaries; route domain rendering to hic-visualization and boundary-feature overlap to genome-intervals.

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Detects A/B chromatin compartments from balanced Hi-C contact matrices via eigenvector decomposition of the distance-normalized, Pearson-correlated cis matrix with cooltools (eigs_cis), then orients (phases) the compartment eigenvector against a GC or gene-density track so the active (A) sign is not arbitrary. Covers the eigenvector-is-a-choice problem (per-arm view_df to remove the centromere gradient; picking the eigenvector by max correlation with activity, not by eigenvalue), GC phasing with bioframe.frac_gc, resolution choice (100kb-1Mb), saddle plots and saddle_strength for compartmentalization strength, the cohesin-loss-strengthens-compartments result, subcompartments (SNIPER/Calder/dcHiC), and cross-condition compartment switching. Use when calling A/B compartments, computing E1/eigenvectors, phasing the eigenvector, building saddle plots, choosing a compartment resolution, quantifying compartment strength, or comparing compartmentalization across conditions.

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Rank and prioritize neoantigen/epitope candidates by likely T-cell response using NeoFox feature annotation, PRIME2.0, BigMHC-IM, the Łuksza/Balachandran fitness model (agretopicity + foreignness), and pVACtools tiering. Encodes the field's hard truths that immunogenicity is the least-solved layer (dedicated scores ~AUROC 0.6-0.7, modest PPV), that scores are valid only for RANKING within one patient (never absolute go/no-go or cross-patient), that DAI has anchor-inflation and WT-denominator traps, and that stacking weak correlated scores into one number is a red flag. Use when ordering a candidate list for a vaccine. Binding lives in mhc-binding-prediction; calling in neoantigen-prediction.

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Calls significant loops from protein-directed and targeted 3C assays (HiChIP, PLAC-seq, Capture Hi-C/PCHi-C, ChIA-PET) where the contact background is peak-anchored and coverage-biased, so generic Hi-C loop callers (cooltools dots, Juicer HiCCUPS) use the wrong null. Covers FitHiChIP (config-driven coverage+distance-decay spline regression, peak-to-peak vs peak-to-all foreground, loose vs stringent background, coverage vs ICE bias), MAPS (positive Poisson regression on bias factors for PLAC-seq/HiChIP), hichipper (restriction-site-distance bias model + library QC), CHiCAGO (Delaporte two-component Brownian+technical background for asymmetric bait x other-end Capture Hi-C), the with/without separate-ChIP anchor decision, and differential loops via diffloop. Use when calling loops from HiChIP/PLAC-seq/Capture Hi-C, choosing FitHiChIP/MAPS/CHiCAGO, picking peak-to-all vs peak-to-peak, setting the loop FDR, supplying ChIP peaks as anchors, QCing a HiChIP library, or comparing loops between conditions.

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Detects acquired antimicrobial-resistance determinants and chromosomal point-mutation resistance in bacterial assemblies using AMRFinderPlus, ResFinder 4.0 (acquired + PointFinder), CARD-RGI, abritAMR, staramr, and species-specific callers (TB-Profiler, Mykrobe). Harmonises cross-tool output via hAMRonization, contextualises determinants with mobile-genetic-element annotation (MOB-suite, PlasmidFinder, MobileElementFinder, ICEberg), predicts phenotype against EUCAST or CLSI breakpoints, and translates calls into WHO GLASS reporting categories. Use when screening clinical or surveillance isolates for AMR, distinguishing acquired vs intrinsic vs point-mutation resistance, calling rpoB / katG / pncA / gyrA / mgrB mutations, reconciling AMRFinderPlus vs RGI vs ResFinder disagreement, contextualising carbapenemases or mcr alleles on plasmids, predicting susceptibility from genotype against the WHO Mtb 2nd-edition catalogue, or building a hAMRonized multi-lab AMR surveillance pipeline.

日本語の概要は準備中です。原文の説明を表示しています。