「signatures」の検索結果

Implement electronic signatures compliant with 21 CFR Part 11 Subpart C and EU Annex 11. Covers signature manifestation (signer, date/time, meaning), signature-to-record binding, biometric vs non-biometric controls, policy creation, and user certification requirements. Use when a computerized system requires legally binding electronic signatures for GxP records, when replacing wet-ink signatures in regulated workflows, when implementing batch release or document approval workflows, or when a regulatory gap reveals missing signature controls.

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Identify recurrent and driver copy number alterations across a tumor cohort with GISTIC2 (G-score, Ziggurat deconstruction, focal vs broad/arm-level analysis, q-values from permutation) and quantify copy-number signatures with the Steele 2022 COSMIC framework and the Drews 2022 CINSignatures framework. Covers driver-gene localization from recurrence peaks, distinguishing focal drivers from arm-level passengers, and the caller-sensitivity caveats of copy-number signatures. Use when finding recurrently amplified or deleted regions in a cohort, localizing driver genes, separating focal from broad events, running GISTIC2, or extracting copy-number mutational signatures.

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Identify recurrent and driver copy number alterations across a tumor cohort with GISTIC2 (G-score, Ziggurat deconstruction, focal vs broad/arm-level analysis, q-values from permutation) and quantify copy-number signatures with the Steele 2022 COSMIC framework and the Drews 2022 CINSignatures framework. Covers driver-gene localization from recurrence peaks, distinguishing focal drivers from arm-level passengers, and the caller-sensitivity caveats of copy-number signatures. Use when finding recurrently amplified or deleted regions in a cohort, localizing driver genes, separating focal from broad events, running GISTIC2, or extracting copy-number mutational signatures.

日本語の概要は準備中です。原文の説明を表示しています。

Identify recurrent and driver copy number alterations across a tumor cohort with GISTIC2 (G-score, Ziggurat deconstruction, focal vs broad/arm-level analysis, q-values from permutation) and quantify copy-number signatures with the Steele 2022 COSMIC framework and the Drews 2022 CINSignatures framework. Covers driver-gene localization from recurrence peaks, distinguishing focal drivers from arm-level passengers, and the caller-sensitivity caveats of copy-number signatures. Use when finding recurrently amplified or deleted regions in a cohort, localizing driver genes, separating focal from broad events, running GISTIC2, or extracting copy-number mutational signatures.

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Ed25519 is a high-performance digital signature algorithm using the Edwards curve Curve25519. It provides 128-bit security with 64-byte signatures and 32-byte keys, offering significant advantages ove

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PDFやOffice文書、画像をNutrient DWS APIで変換・加工するスキル。文字や表の抽出、スキャンの文字認識、機密情報の墨消し、署名やフォーム入力を扱います。

• Office文書やHTMLのPDF化
• スキャン文書を検索したいとき
• PDFの表をExcelに取り出したいとき

Automate Esignatures IO tasks via Rube MCP (Composio). Always search tools first for current schemas.

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Detect network reconnaissance and port scanning using Suricata and Snort IDS signatures, threshold-based detection rules, and traffic anomaly analysis to identify Nmap, Masscan, and custom scanning activity.

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Identify poisoned training data and backdoored ML models across the pipeline using IBM's Adversarial Robustness Toolbox (activation clustering, spectral signatures, trigger reconstruction), Cleanlab for label-quality issues, and supply-chain checks like weight-hash verification and safetensors enforcement. Use before training or deploying on third-party/user-contributed data or downloaded checkpoints, during ML supply-chain reviews, or when investigating model misbehavior tied to specific inputs (suspected backdoor trigger).

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Parse and analyze Cobalt Strike Malleable C2 profiles with dissect.cobaltstrike (profiles and beacon-payload configs) and pyMalleableC2 (AST parsing) to extract HTTP/DNS transforms, URIs, headers, sleep/jitter, and injection behavior, then generate network detection signatures. Use when reverse-engineering a captured malleable profile or building detections against Cobalt Strike Beacon traffic.

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Search auto-generated codebase documentation for function signatures, API docs, class definitions, and code comments. Use when the user asks to "search docs", "find documentation", "look up a function", "check the API", or before implementing changes to verify correct signatures and patterns.

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Extract and analyze mutational signatures from somatic variants using SigProfiler or MutationalPatterns to characterize mutagenic processes. Use when identifying DNA damage mechanisms or etiology in cancer genomes.

日本語の概要は準備中です。原文の説明を表示しています。

Extracts and assigns COSMIC v3.4 mutational signatures (86 SBS / 11 DBS / 18 ID / 21 CN / 16 SV) from somatic VCFs using SigProfilerSuite, MutationalPatterns, MuSiCal mvNMF, SigNet, or HRDetect. Use when characterizing DNA-damage etiology (BRCA1/2 HRD, MMR-D, POLE, APOBEC3A, UV, tobacco, aflatoxin, 5-FU/SBS17b, platinum, colibactin SBS88), routing PARP inhibitor decisions, or auditing de novo extraction vs refit choice for cohort size.

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Generate SuperSigs (supervised mutational signatures) from single nucleotide variants in the cancer genome. Functions included in the package allow the user to learn supervised mutational signatures from their data and apply them to new data. The methodology is based on the one described in Afsari (2021, ELife).

日本語の概要は準備中です。原文の説明を表示しています。

Programmatic inbox management for Smartlead. Enable/disable warmup with correct ramp settings, set signatures in bulk, tag inboxes (active vs insurance), and pull inbox health dashboards. Use after creating a new batch of inboxes via /zapmail-domain-setup-public, or when managing an existing Smartlead account at scale. Triggers on "turn on warmup", "set signatures", "tag inboxes", "inbox health", "set up new inboxes".

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Validate API consistency between two versions of Python libraries. Use when you need to compare API behavior, signatures, and exceptions between library versions to identify breaking changes, incompatible modifications, and behavior differences. The skill performs static analysis of Python code, compares function signatures, class definitions, parameter types, return types, and generates a detailed JSON report with breaking changes, warnings, and migration guidance. Supports Python libraries and packages.

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Validate API consistency between two versions of Java libraries. Use when you need to compare API behavior, signatures, and exceptions between Java library versions to identify breaking changes, incompatible modifications, and behavior differences. The skill performs static analysis of Java code, compares method signatures, class definitions, interface changes, parameter types, return types, exception declarations, and generates a detailed JSON report with breaking changes, warnings, and migration guidance. Supports Java libraries and packages.

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DSPy is a Python framework from Stanford NLP that replaces hand-written prompts with code: you declare LLM tasks as typed signatures, compose them into modules, and let optimizers (BootstrapFewShot, MIPROv2, GEPA) tune the prompts and few-shot examples against your metric. Use when the user asks about DSPy, signatures, ChainOfThought, ReAct, teleprompters or optimizers, or wants to stop hand-tuning prompts.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes Windows Authenticode signatures on PE files: checking for a signature, reading the signer certificate chain, detecting revoked/expired/stolen certs, and recognizing signature-stripping and catalog-signing abuse. Activates for requests to analyze a code signature, verify Authenticode, or assess signer trust on a PE.

日本語の概要は準備中です。原文の説明を表示しています。

Digital signatures and time stamps through Openapi - eIDAS-compliant electronic signatures (SES with OTP, qualified QES, e-seals, massive automatic signing) and qualified time stamping of documents. Use when the user needs a document signed electronically or time-stamped with legal validity.

日本語の概要は準備中です。原文の説明を表示しています。

Extracts and assigns COSMIC v3.4 mutational signatures (86 SBS / 11 DBS / 18 ID / 21 CN / 16 SV) from somatic VCFs using SigProfilerSuite, MutationalPatterns, MuSiCal mvNMF, SigNet, or HRDetect. Use when characterizing DNA-damage etiology (BRCA1/2 HRD, MMR-D, POLE, APOBEC3A, UV, tobacco, aflatoxin, 5-FU/SBS17b, platinum, colibactin SBS88), routing PARP inhibitor decisions, or auditing de novo extraction vs refit choice for cohort size.

日本語の概要は準備中です。原文の説明を表示しています。

Generate, fill, and assemble PDF documents at scale. Handles legal forms, contracts, invoices, certificates. Supports form filling (pdf-lib), template rendering (Puppeteer, LaTeX), digital signatures (DocuSign), and document assembly. Use for legal tech, HR automation, invoice generation. Activate on "PDF generation", "form filling", "document automation", "digital signatures". NOT for simple PDF viewing, basic file conversion, or OCR text extraction.

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Expert-level exoplanet science covering detection methods, orbital dynamics, planetary atmospheres, habitability, and the search for biosignatures.

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Use when you need to inspect NuGet package APIs, list public types, or decompile method/property signatures. Keywords: inspect package API, list types, decompile type, method signatures, NuGet interface.

日本語の概要は準備中です。原文の説明を表示しています。