AI-powered adeno-associated virus (AAV) vector design for gene therapy including capsid engineering, promoter selection, and tropism optimization.
日本語の概要は準備中です。原文の説明を表示しています。
Implement proven backend architecture patterns including Clean Architecture, Hexagonal Architecture, and Domain-Driven Design. Use this skill when designing clean architecture for a new microservice, when refactoring a monolith to use bounded contexts, when implementing hexagonal or onion architecture patterns, or when debugging dependency cycles between application layers.
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Master proven backend architecture patterns including Clean Architecture, Hexagonal Architecture, and Domain-Driven Design to build maintainable, testable, and scalable systems.
Given: a service boundary or module to architect. Produces: layered structure with clear dependency rules, interface definitions, and test boundaries.
Layers (dependency flows inward):
Key Principles:
Components:
Benefits:
Strategic Patterns:
Tactical Patterns:
Detailed pattern documentation lives in references/details.md. Read that file when the navigation tier above is insufficient.
The hallmark of correctly applied Clean Architecture is that every use case can be exercised in a plain unit test with no real database, no Docker, and no network:
# tests/unit/test_create_user.py
import asyncio
from typing import Dict, Optional
from domain.entities.user import User
from domain.interfaces.user_repository import IUserRepository
from use_cases.create_user import CreateUserUseCase, CreateUserRequest
class InMemoryUserRepository(IUserRepository):
def __init__(self):
self._store: Dict[str, User] = {}
async def find_by_id(self, user_id: str) -> Optional[User]:
return self._store.get(user_id)
async def find_by_email(self, email: str) -> Optional[User]:
return next((u for u in self._store.values() if u.email == email), None)
async def save(self, user: User) -> User:
self._store[user.id] = user
return user
async def delete(self, user_id: str) -> bool:
return self._store.pop(user_id, None) is not None
async def test_create_user_succeeds():
repo = InMemoryUserRepository()
use_case = CreateUserUseCase(user_repository=repo)
response = await use_case.execute(CreateUserRequest(email="alice@example.com", name="Alice"))
assert response.success
assert response.user.email == "alice@example.com"
assert response.user.id is not None
async def test_duplicate_email_rejected():
repo = InMemoryUserRepository()
use_case = CreateUserUseCase(user_repository=repo)
await use_case.execute(CreateUserRequest(email="alice@example.com", name="Alice"))
response = await use_case.execute(CreateUserRequest(email="alice@example.com", name="Alice2"))
assert not response.success
assert "already exists" in response.error
Business logic has leaked into the infrastructure layer. Move all database calls behind an IRepository interface and inject an in-memory implementation in tests (see Testing section above). The use case constructor must accept the abstract port, not the concrete class.
A common symptom is ImportError: cannot import name X between use_cases and adapters. This happens when a use case imports a concrete adapter class instead of the abstract port. Enforce the rule: use_cases/ imports only from domain/ (entities and interfaces). It must never import from adapters/ or infrastructure/.
If SQLAlchemy Column() or Pydantic Field() annotations appear on domain entities, the entity is no longer pure. Create a separate ORM model in adapters/repositories/ and map to/from the domain entity in the repository's _to_entity() method.
When the controller grows beyond HTTP parsing and response formatting, extract the logic into a use case class. A controller method should do three things only: parse the request, call a use case, map the response.
Validate invariants in __post_init__ (Python) or the constructor so an invalid Email or Money cannot be constructed at all. This surfaces bad data at the boundary, not deep inside business logic.
If the Order context is importing User entities from the Identity context, introduce an Anti-Corruption Layer. The Order context should hold its own lightweight CustomerId value object and only call the Identity context through an explicit interface.
For detailed DDD bounded context mapping, full multi-service project trees, Anti-Corruption Layer implementations, and Onion Architecture comparisons, see:
microservices-patterns — Apply these architecture patterns when decomposing a monolith into servicescqrs-implementation — Use Clean Architecture as the structural foundation for CQRS command/query separationsaga-orchestration — Sagas require well-defined aggregate boundaries, which DDD tactical patterns provideevent-store-design — Domain events produced by aggregates feed directly into an event storeまだレビューはありません。使ってみた感想をお寄せください。
概要と使いどころ
AI-powered adeno-associated virus (AAV) vector design for gene therapy including capsid engineering, promoter selection, and tropism optimization.
日本語の概要は準備中です。原文の説明を表示しています。
Improve the clarity and voice of AI-assisted academic writing (papers, theses, rebuttals) and
日本語の概要は準備中です。原文の説明を表示しています。
12-agent academic paper writing pipeline. 11 modes (full/plan/outline/revision/revision-coach/abstract/lit-review/format-convert/citation-check/disclosure/rebuttal-audit). 6 paper types, 5 citation formats, bilingual abstracts, LaTeX/DOCX-via-Pandoc/PDF output. Style Calibration + Writing Quality Check + Anti-Patterns with IRON RULE markers. Triggers: write paper, academic paper, guide my paper, parse reviews, audit my rebuttal, check my response draft, AI disclosure, 寫論文, 學術論文, 引導我寫論文, 審查意見, 評估回覆, 논문 작성, 초록 작성, 논문 수정, 논문 계획을 도와줘, 심사 의견 반영, 답변서 점검, AI 사용 고지.
日本語の概要は準備中です。原文の説明を表示しています。
Systematic writing framework for philosophy and interdisciplinary academic papers from optimized outline to submission-ready manuscript. Use when users want to: (1) write a paper from a detailed outline, (2) ensure quality control during writing, (3) maintain consistency across chapters, (4) prepare a submission-ready manuscript, or (5) systematically execute a planned paper. Triggered by phrases like 'write the paper from this outline,' 'compose the full manuscript,' 'execute the outline,' or when users have completed strategic planning (academic-paper-strategist skill) and are ready to write. Takes optimized outline as input; outputs complete manuscript with iterative quality checks.
日本語の概要は準備中です。原文の説明を表示しています。
Multi-perspective academic paper review with dynamic reviewer personas. Runs a 5-seat, role-separated review panel (Journal-Fit Reviewer + 3 peer-review roles + Devil's Advocate) with field-specific expertise; role separation is not a claim of independent error processes. Supports full review, re-review (verification), quick assessment, methodology focus, Socratic guided, and calibration modes. Triggers on: review paper, peer review, manuscript review, referee report, review my paper, critique paper, simulate review, editorial review, calibrate reviewer, reviewer calibration, measure reviewer accuracy, 審查論文, 論文審查, 模擬審查, 同儕審查, 幫我審這篇, 以審查人角度評估, 審查者校準, 논문 심사, 동료 심사, 모의 심사, 심사자 관점에서 평가, 심사자 보정.
日本語の概要は準備中です。原文の説明を表示しています。
Systematic strategic planning framework for philosophy and interdisciplinary academic papers targeting preprint platforms (PhilArchive, arXiv, PhilSci-Archive). Use when users want to: (1) plan a paper on a specific topic, (2) identify research gaps and assess originality, (3) develop optimized paper outlines, (4) prepare for preprint submission, or (5) understand platform requirements and writing standards. Triggered by phrases like 'plan a paper on,' 'help me design a paper about,' 'identify research gaps in,' 'is this idea original,' or when users need structured research planning. The skill guides through three phases: Platform Analysis (identifying target venue and studying sample papers), Theoretical Framework (AI-driven literature search and gap identification), and Outline Optimization (structured design with reviewer-perspective self-assessment). Each phase includes quality evaluation standards and validation checkpoints.
日本語の概要は準備中です。原文の説明を表示しています。