「interpretation」の検索結果

Queries gnomAD v4 (807k samples), v3, v2.1.1, and constraint metrics with grpmax FAF95, bottleneck-group exclusion, LOEUF interpretation, SV/CNV/mtDNA catalogs, and Whiffin max-credible-AF framework. Use when filtering rare variants, applying ACMG BS1/BA1, ranking genes by LoF intolerance, or selecting between v2 (GRCh37 + chrX/Y constraint) and v4 (GRCh38 + 807k samples).

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Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.

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Codified expertise for quality control, non-conformance investigation, root cause analysis, corrective action, and supplier quality management in regulated manufacturing. Informed by quality engineers with 15+ years experience across FDA, IATF 16949, and AS9100 environments. Includes NCR lifecycle management, CAPA systems, SPC interpretation, and audit methodology. Use when investigating non-conformances, performing root cause analysis, managing CAPAs, interpreting SPC data, or handling supplier quality issues.

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Local-first year-round tax memory system for individuals, freelancers, and small businesses. Use when users mention tax documents, receipts, expenses, tax notices, filing preparation, missing forms, accountant meetings, or year-end organization. Captures tax-relevant facts as they happen, tracks what may be missing, and prepares CPA-ready handoff summaries. NEVER provides tax advice, legal interpretations, filing positions, or final tax calculations.

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Professional Ziwei Doushu consultation skill with offline, Beijing-standard calculation rules. Use when the user wants a polished Ziwei report from birth date and time, including life palace structure, twelve palaces, four transformations, major luck cycles, yearly triggers, optional chart images, and a clear split between chart facts and traditional interpretation.

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Captures clause risks, compliance gaps, precedent shifts, contract deviations, regulatory changes, and litigation exposure to enable continuous legal operations improvement. Use when: (1) An unfavorable clause is accepted or slips through review, (2) A compliance deadline is missed or approaching, (3) A new regulation impacts the organization, (4) A contract remains unsigned past SLA, (5) An IP infringement notice is received, (6) New case law changes interpretation in a relevant jurisdiction, (7) A data subject access request reveals process gaps.

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A Vedic astrology (Jyotish) analyzer based on the Indian Jyotish tradition, using the Sidereal zodiac to read birth charts. Covers 27 Nakshatras (Lunar Mansions), the Vimshottari Dasha (Major Period) system, and the Navagraha (Nine Planets). Triggered when users mention "Vedic astrology," "Jyotish," "Vedic," "Nakshatra," "Dasha," or "Indian astrology." Pure LLM reasoning for interpretation (precise charts require an astronomical engine). No external API required. Not applicable for: Western astrology horoscopes, BaZi, tarot, Zi Wei Dou Shu, or other domains → use the fortune-hub router instead.

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按关键词检索周公解梦释义，支持分页。当用户说：梦见蛇是什么意思？梦到飞代表什么？或类似解梦问题时，使用本技能。

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中国法律法规查询工具。Use when user needs to search Chinese laws, regulations, judicial interpretations. Supports criminal law, civil law, labor law, contract law, intellectual property law. 中国法律、法规查询、法律条文。

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Complete guide for code coverage analysis. Use when you need to analyze code coverage, generate coverage reports, or configure CI/CD coverage checks. Covers Coverlet configuration, report generation, metric interpretation, and cyclomatic complexity integration. Includes Fine Code Coverage, VS Code built-in tools, and best practices. Keywords: code coverage, coverage analysis, coverage report, Coverlet, Fine Code Coverage, dotnet-coverage, ReportGenerator, line coverage, branch coverage, cyclomatic complexity, runsettings, cobertura

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PR test analysis routing. Use for pull request or diff test impact, changed-test review, CI failure interpretation, and focused test matrix recommendations; do not use for general code review or editing tests.

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