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Structure prediction for protein, nucleic-acid, and small-molecule complexes with the Chai-1 foundation model (Chai Discovery 2024, github.com/chaidiscovery/chai-lab). Reach for this skill to predict an antibody-antigen or protein-ligand complex from a single FASTA, to re-fold designed binders as an AlphaFold-multimer alternative, or to drive co-folding from Python for batched campaigns on a GPU.

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Prepare azd-based Azure projects for deployment: generates azure.yaml, infrastructure (Bicep/Terraform), and Dockerfiles for the Azure Developer CLI (azd) workflow. USE ONLY when the user explicitly wants to use azd as the deployment tool, or the project already has an azure.yaml file. DO NOT USE FOR: non-azd deployments, Python App Service code-only deploys (use python-appservice-deploy), or cross-cloud migration (use azure-cloud-migrate). WHEN: prepare app for azd, create azure.yaml, set up azd infrastructure, modernize app for Azure with azd, deploy with azd, function app, timer trigger, service bus trigger, event-driven function, managed identity, generate Bicep, generate Terraform, create and deploy to Azure.

日本語の概要は準備中です。原文の説明を表示しています。

Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm. For QC thresholds, use protein-qc.

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Set up recurring or scheduled work — anything the user wants run on a schedule, repeatedly, or at a future time ("every morning", "each weekday at 9am", "daily digest", "weekly report", "remind me", "run this on a cron"). Teaches how to author a durable Vexa Scheduler routine that survives restarts. Use this instead of any OS cron job, system timer, or session-only reminder.

日本語の概要は準備中です。原文の説明を表示しています。

Prepare azd-based Azure projects for deployment: generates azure.yaml, infrastructure (Bicep/Terraform), and Dockerfiles for the Azure Developer CLI (azd) workflow. USE ONLY when the user explicitly wants to use azd as the deployment tool, or the project already has an azure.yaml file. DO NOT USE FOR: non-azd deployments, Python App Service code-only deploys (use python-appservice-deploy), or cross-cloud migration (use azure-cloud-migrate). WHEN: prepare app for azd, create azure.yaml, set up azd infrastructure, modernize app for Azure with azd, deploy with azd, function app, timer trigger, service bus trigger, event-driven function, managed identity, generate Bicep, generate Terraform, create and deploy to Azure.

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Force the states a happy-path run never reaches (a failing API, an empty list, a slow request, a timeout, an expired session, a toast that auto-dismisses) and check the UI actually handles them. Use when error handling was written but never run, when a loading or empty state needs verifying, when a bug only happens on a slow connection, or when a timer, poll, debounce or retry needs testing without sleeping.

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Use when work crosses into Apple's system surfaces rather than your own UI or data — Siri and Shortcuts, widgets, Live Activities, in-app purchase, localization, privacy prompts, alarms, timers, calendar, reminders, contacts, SharePlay, VoIP and CallKit, accessory pairing, weather, Spotlight indexing, background tasks, Background Assets, push, or push on networks with no internet.

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Use when the user mentions memory leak prevention, code review for memory issues, or proactive leak checking — retain cycles, leaks, and Timer/observer patterns.

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Use when the user mentions battery drain, energy optimization, power consumption audit, or pre-release energy check — timer abuse, polling patterns, continuous location, animation leaks, and background mode misuse.

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Implement, review, or improve Live Activities and Dynamic Island experiences in iOS apps using ActivityKit. Use when building real-time updating widgets for the Lock Screen and Dynamic Island — delivery tracking, sports scores, ride-sharing status, workout timers, media playback, or any time-sensitive information that updates in real time. Also use when working with ActivityKit, ActivityAttributes, Activity lifecycle (request/update/end), Dynamic Island layouts (compact/minimal/expanded), push-to-update Live Activities, or Lock Screen live widgets.

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Create and manage systemd services and timers. Configure service dependencies and resource limits. Use when managing system services.

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Model, simulate, and optimize Serializer/Deserializer (SerDes) systems — serial and parallel links — using MATLAB SerDes Toolbox. Design NRZ and PAM-N links (PAM3 through PAM16) — explore equalization architectures (FFE, CTLE, DFE), sweep or optimize parameters with genetic algorithms, and characterize channels from loss models, S-parameter files, or crosstalk scenarios. Process captured waveforms through equalization chains, build eye diagrams, and decompose jitter. Deliver IBIS-AMI models for Tx, Rx, Redriver, or Retimer by exporting to Simulink and compiling .ami/.ibs/.dll/.so files. Covers the full arc from initial design exploration and parameter optimization to compliance testing and compiled model validation, including custom datapath blocks for nonstandard equalization.

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Establish MAVLink connections between MATLAB and PX4/ArduPilot autopilots. Use when connecting to a drone, flight controller, or autopilot via MAVLink protocol over UDP. Covers dialect setup, UDP transport, timer-based heartbeat, and client discovery. Use when: "connect to PX4", "MAVLink connection", "heartbeat", "ground control station", "GCS", "connect to ArduPilot", "drone communication", "mavlinkio", "SITL".

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Builds a high-fidelity interactive legal assessment as a single self-contained HTML artifact. Output includes a live countdown timer, contract review tasks with hover-annotated problem clauses, candidate answer textareas, model answers hidden behind reveal blocks, scenario-based legal memo tasks, strategy and function-building questions, and a pre-submission checklist that encodes the marking criteria. Use when the user needs to (1) assess a legal candidate with a realistic timed exercise, (2) train or onboard junior lawyers using problem sets rather than doctrine, (3) help a candidate prepare for a real take-home assessment they are facing, (4) build educational materials for law students, in-house teams, or compliance training, or (5) produce scenario-based training modules on specific legal topics. Triggers on "legal test", "take-home", "mock exam", "contract redline exercise", "candidate assessment", "legal training exercise", "practice test", or similar phrasing even when informal.

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Audit a project's infrastructure and SaaS stack, then produce a cost report showing what the user currently pays and what they would save by consolidating onto Temps (self-hosted or Temps Cloud). Detects hosting platforms (Vercel, Netlify, Railway, Render, Heroku, Fly.io), analytics (PostHog, Plausible, Mixpanel, Amplitude, Fathom), error tracking (Sentry, Bugsnag, Rollbar, Honeybadger), session replay (LogRocket, FullStory, Hotjar, Highlight), uptime monitoring (Pingdom, UptimeRobot, Better Stack, Checkly), managed databases (Supabase, Neon, PlanetScale, MongoDB Atlas, Upstash, RDS), and transactional email (SendGrid, Postmark, Resend, Mailgun) from dependencies, config files, and env var names. Use when the user wants to: (1) Know how much they would save by switching to Temps, (2) Audit their SaaS/infrastructure spend, (3) Compare their current stack's cost against self-hosting, (4) Decide whether Temps is worth it, (5) Build a business case for consolidating tools. Triggers: "how much would I save", "temps savings", "cost comparison", "audit my stack", "am I overpaying", "saas spend", "calculate savings", "is temps cheaper".

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Build a webinar or live event registration page as a self-contained HTML file with countdown timer, speaker bio, agenda, and registration form. Triggers on: "build a webinar registration page", "create a webinar sign-up page", "event registration landing page", "live training registration page", "workshop sign-up page", "create a webinar page", "build an event page", "free webinar landing page", "live demo registration page", "online event page", "create a registration page for my webinar", "build a training event page".

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Design Microsoft Orleans systems from each primitive's purpose and failure model. USE FOR: grains, digital twins, state versus databases, transactions, messaging, streams, timers, reminders, Durable Jobs, stateless workers, grain services, startup, and hosting. DO NOT USE FOR: other actor stacks, batches, relational-only CRUD, or advice without an Orleans decision. INVOKES: inspect version and topology, choose the primitive, implement, and validate.

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Schedules work in Convex: cron jobs in convex/crons.ts, one off scheduled functions with runAfter and runAt, batching large jobs, and cancelling or inspecting the queue. Use when something needs to run on a timer, later, or in the background, or when a cron is not firing.

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Write, review, filter, mock, and debug Core unit tests with the repository's installed Vitest 5 configuration. Use for tests under Core's Vitest include paths, `vi.mock`/spies/timers, jsdom component tests, coverage output, focused reruns, or unit-test failures. Do not use for browser E2E flows or async Next.js Server Components.

日本語の概要は準備中です。原文の説明を表示しています。

Schedule AI agent runs with cron, loops, or external clocks while avoiding unsafe tight autonomous timers.

日本語の概要は準備中です。原文の説明を表示しています。

Fix Riverpod "Cannot use Ref or modify other providers inside life-cycles/selectors" crash in @riverpod provider bodies. Use when: (1) Crash during provider disposal with this exact error message, (2) Using keepAlive() with timer-based disposal, (3) Async callbacks (.then, .catchError) try to use ref.read() or ref.invalidateSelf(), (4) Error occurs after ref.onCancel/onResume/onDispose callbacks fire. Solution: wrap ref operations in try-catch or avoid using ref in async callbacks entirely.

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Chai-1 structure prediction for protein complexes and design validation. Use this skill when: (1) Predicting protein-protein complex structures, (2) Validating designed binders, (3) Predicting protein-ligand complexes, (4) Using the Chai API for high-throughput prediction, (5) Need an alternative to AlphaFold2. For QC thresholds, use protein-design-qc. For AlphaFold2 prediction, use alphafold2-multimer. For ESM-based analysis, use esm2-sequence-scoring.

日本語の概要は準備中です。原文の説明を表示しています。

Boltz-1 / Boltz-2 structure prediction for proteins, complexes, and ligand-aware validation. Use this skill when: (1) Predicting protein complex structures, (2) Validating designed binders, (3) Need open-source alternative to AF2, (4) Predicting protein-ligand complexes, (5) Using local GPU resources. For QC thresholds, use protein-design-qc. For AlphaFold2 prediction, use alphafold2-multimer. For Chai prediction, use chai1-structure-prediction.

日本語の概要は準備中です。原文の説明を表示しています。

Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm. For QC thresholds, use protein-qc.

日本語の概要は準備中です。原文の説明を表示しています。